VIOLIN: Vaccine Investigation and Online Information Network

TC0757 hypothetical protein

General Information

Protegen ID

431

Sequence Strain (Species/Organism)

Chlamydia muridarum str. Nigg

VO ID

VO_0010886

Taxonomy ID

243161

Molecule Role

Protective antigen

Molecule Role Annotation

Following vaginal challenge with live Chlamydia, the groups of female BALB/c mice immunized intra-abdominally with TC0757 showed significant levels of protection when compared to negative control animals (McNeilly et al., 2007).

Related Vaccines(s)

C. muridarum DNA vaccine encoding TC0757

References

McNeilly et al., 2007: McNeilly CL, Beagley KW, Moore RJ, Haring V, Timms P, Hafner LM. Expression library immunization confers partial protection against Chlamydia muridarum genital infection. Vaccine. 2007; 25(14); 2643-2655. [PubMed: 17239501].

Gene Information

Gene Name

TC0757 hypothetical protein

NCBI Gene ID

1246122

Genbank Accession

AE002160

Locus Tag

TC_RS03850

Gene Starting Position

898853

Gene Ending Position

899647

DNA Sequence

>NC_002620.2:898853-899647 Chlamydia muridarum Nigg, complete genome
CATGCGCTGTTCTGCTTATTGCTCTGCTTCGTCCTATCATCTACACGTTCTTTTTCATCTTTTAAAGGCA
CGCTACCCTTCTGTCTTATCCCGAGAATACGTGCTCATTTCCTCTGAAGAGCTGAATGAAAGCGACAAAG
CCGCTGTCTTTTTCCCATTTGGAGTTAGTGTGTTTTGGGGATGGGAAGAAGCTGAAGAACTTCAAGTGAT
CCAAGCTATCACCTCAGCATCAGTGGATCCTCTCCCTAACCCAGAAATTGATAGTTATGACTTCCATTAT
GGAGAGAAACTACAGATCCGTCGCGATAGACTTGTTCTCACCAACTCTAATTTAAACACAAAACTTGCTA
TTTCCTTTGGGTTAGCCCAATCTATCAAACTTACCGTCTTTGAAGAAACGATTTACAAAACAGTTGAAAA
CTCTAAATCTTTGCCTCAAGAACTTGCCTCTAAAGGGAAAATTTCTCTATCCCGTAAAACGATCGCAAAA
AAGATTGGAGAGCTTTTCCTGGATAAAGCTTCCGTAAACCTACACTCTGACATTCTCGATGAGCCCGACT
TTTTCTGGGAACATCCAGAAACCCAACCTTTTTATATTGATGTGTTGACCTGCCTAGATGTAAACGCGCG
AGTAAATGTATTAAATCACAGACTTGCTATCCTAGGAGATGTTCTCGAGATTTTAAATGACCAACTTAAT
CATCAGCATTCTTCAGCTCTAGAGTGGACCGTGATCTGGTTAATTGCACTAGAGGTATTGGTCACCTTAC
TTAAAGACGTATTCAACATCATCTA

Protein Information

Protein Name

hypothetical protein

NCBI Protein GI

497917305

Protein Accession

WP_010231461

Protein pI

5.02

Protein Weight

27979.63

Protein Length

264

Protein Note

identified by match to TIGR protein family HMM TIGR01607

Protein Sequence

>WP_010231461.1 RMD1 family protein [Chlamydia muridarum]
MRCSAYCSASSYHLHVLFHLLKARYPSVLSREYVLISSEELNESDKAAVFFPFGVSVFWGWEEAEELQVI
QAITSASVDPLPNPEIDSYDFHYGEKLQIRRDRLVLTNSNLNTKLAISFGLAQSIKLTVFEETIYKTVEN
SKSLPQELASKGKISLSRKTIAKKIGELFLDKASVNLHSDILDEPDFFWEHPETQPFYIDVLTCLDVNAR
VNVLNHRLAILGDVLEILNDQLNHQHSSALEWTVIWLIALEVLVTLLKDVFNII

Epitope Information

IEDB Linear Epitope