Rop2
General Information
Protegen ID
4347
Sequence Strain (Species/Organism)
Toxoplasma gondii
Taxonomy ID
5811
Other Database IDs
CDD:291215 CDD:304357
Molecule Role
Protective antigen
Molecule Role Annotation
(Picchio et al. , 2018 )
References
Picchio et al. , 2018: Picchio MS, Sánchez VR, Arcon N, Soto AS, Perrone Sibilia M, Aldirico MLA, Urrutia M, Moretta R, Fenoy IM, Goldman A, Martin V. Vaccine potential of antigen cocktails composed of recombinant Toxoplasma gondii TgPI-1, ROP2 and GRA4 proteins against chronic toxoplasmosis in C3H mice. Experimental parasitology . 2018; 185; 62-70. [PubMed: 29309783 ].
Gene Information
Gene Name
Rop2
Protein Information
Protein Name
Rop2 protein
NCBI Protein GI
ABI93795
Protein pI
9.64
Protein Weight
28699.38
Protein Length
316
Protein Note
Kinase-like; pfam14531
Protein Sequence
>ABI93795.1 Rop2 protein, partial [Toxoplasma gondii]
LRLLRGIKNQKQAKVHLRFIFPFDLVKDPKKRKMIRVRLDERDMWVLSRFFLYPRMQSNLQMLGDVLLSH
SSTHKSLVHHARLQLTLQLIRLLASLHHYGLVHADFQVSNILLDQRGGVFLTGFEHLVRDGASAVSPIGR
GFAPPETTAERMLPFGQHHPTLMTFAFDTWTLGLAIYWIWCADLPNTDDAALGGSEWIFRSCKNIPQPVR
ALLEGFLRYPKEDRLLPLQAMETPEYEQLRTELSAVLPLYQTDGEPA
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
540744
ASLHHYGLVH
H2-b class I
94
104
IEDB ID
Epitope
Starting position
Ending position
LRLLRGIKNQKQAKVHLRFIFPFDLVKDPKKRKMIRVRLDERDMWVLSRFFLYPRMQSNLQMLGDVLLSHSSTHKSLVHHARLQLTLQLIRLLASLHHYGLVHADFQVSNILLDQRGGVFLTGFEHLVRDGASAVSPIGRGFAPPETTAERMLPFGQHHPTLMTFAFDTWTLGLAIYWIWCADLPNTDDAALGGSEWIFRSCKNIPQPVRALLEGFLRYPKEDRLLPLQAMETPEYEQLRTELSAVLPLYQTDGEPA