VIOLIN: Vaccine Investigation and Online Information Network

GRA2

General Information

Protegen ID

4348

Sequence Strain (Species/Organism)

Toxoplasma gondii

Taxonomy ID

508771

Molecule Role

Protective antigen

Molecule Role Annotation

(Ching et al., 2017)

References

Ching et al., 2017: Ching XT, Fong MY, Lau YL. Evaluation of the Protective Effect of Deoxyribonucleic Acid Vaccines Encoding Granule Antigen 2 and 5 Against Acute Toxoplasmosis in BALB/c Mice. The American journal of tropical medicine and hygiene. 2017; 96(6); 1441-1447. [PubMed: 28719288].

Gene Information

Gene Name

GRA2

NCBI Gene ID

7897424

Protein Information

Protein Name

dense granule protein GRA2

NCBI Protein GI

EPT27242

Protein pI

9.71

Protein Weight

18298.13

Protein Length

253

Protein Note

encoded by transcript TGME49_227620;
Signal peptide predicted by SignalP 2.0 HMM (probability 0.997) with cleavage site probability 0.917 at residue 23;
GO_component: GO:0020003 - symbiont-containing vacuole;ev_code=EXP;
GO_component: GO:0045177 - apical part of cell;ev_code=EXP

Protein Sequence

>EPT27242.1 dense granule protein GRA2 [Toxoplasma gondii ME49]
MFAVKHCLLVVAVGALVNVSVRAAEFSGVVNQGPVDVPFSGKPLDERAVGGKGEHTPPLPDERQQEPEEP
VSQRASRVAEQLFRKFLKFAENVGQHSEKAFKKAKVVAEKGFTAAKTHTVRGFKVAKEAAGRGMVTVGKK
LANVESDRSTTTTQAPDSPNGLAETQAPVEPQQRAAHVPVPDFSQ

Epitope Information

IEDB Linear Epitope