VIOLIN: Vaccine Investigation and Online Information Network

cofactor-independent phosphoglycerate mutase

General Information

Protegen ID

4360

Sequence Strain (Species/Organism)

Leishmania donovani

Taxonomy ID

5661

Other Database IDs

CDD:215295
CDD:293734

Molecule Role

Protective antigen

Molecule Role Annotation

(Singh et al., 2018)

References

Singh et al., 2018: Singh MK, Jamal F, Dubey AK, Shivam P, Kumari S, Pushpanjali, Ahmed G, Dikhit MR, Narayan S, Das VNR, Pandey K, Sinha KK, Das P, Singh SK. Co-factor-independent phosphoglycerate mutase of Leishmania donovani modulates macrophage signalling and promotes T-cell repertoires bearing epitopes for both MHC-I and MHC-II. Parasitology. 2018; 145(3); 292-306. [PubMed: 29140228].

Gene Information

Gene Name

cofactor-independent phosphoglycerate mutase

NCBI Gene ID

13386661

Protein Information

Protein Name

cofactor-independent phosphoglycerate mutase

NCBI Protein GI

ADG96010

Protein pI

5.52

Protein Weight

56341.08

Protein Length

650

Protein Note

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Protein Sequence

>ADG96010.1 cofactor-independent phosphoglycerate mutase, partial [Leishmania donovani]
MSALLLKLHKDLPRRKLLIVVMDGLGIGPEDDYDAVHMASTPFMDAQRQNSRHFRSVRAHGAAVGLPTDA
DMGNSEVGHNALGAGRVVLQGASLVDDALKSGEIFTGEGYRYLLGAFSKEDSTLHLIGLLSDGGVHSRDN
QIYSIIERAAKDGAKRIRVHVLYDGRDVPDGSSFRFTEELEAVLAKLRQNGCDAAVASGGGRMFVTMDRY
EADWSIVERGWKAQVLGDARHFRSAKEAITTFREEDPKVTDQYYPPFVVVDEQDKPLGTIEDGDAVLCVN
FRGDRVIEMTRAFEDEDFAKFDRVRVPKVRYAGMMRYDGDLGIPNNFLVPPPKLTRVSEEYLCGSGLKIF
ACSETQKFGHVTYFWNGNRSGKIDDEHETFKEVPSDRVHFNKQPKMKSAEITEAAIEALKSGMYDVVRIN
FPNGDMVGHTGDLKATIVGVQAVDESLAKLKDAVDNVNGVFIVTADHGNSDDMAQRDKKGKPIKDGKGNV
LPLTSHTLSPVPVFIGGAGLDPRVKMRTDMPTAGLANVTATFINLLGFEAPEDYEPSLIYVEK

Epitope Information

IEDB Linear Epitope