ribosomal protein L5
General Information
Protegen ID
4364
Sequence Strain (Species/Organism)
Leishmania major
Taxonomy ID
347515
Other Database IDs
CDD:240254 CDD:279233 CDD:238246 CDD:290906 GOA:E9AF09 InterPro: IPR005484 InterPro: IPR005485 InterPro: IPR025607 UniProtKB/TrEMBL: E9AF09
Molecule Role
Protective antigen
Molecule Role Annotation
(Ramirez et al. , 2014 )
References
Ramirez et al. , 2014: Ramirez L, Corvo L, Duarte MC, Chávez-Fumagalli MA, Valadares DG, Santos DM, de Oliveira CI, Escutia MR, Alonso C, Bonay P, Tavares CA, Coelho EA, Soto M. Cross-protective effect of a combined L5 plus L3 Leishmania major ribosomal protein based vaccine combined with a Th1 adjuvant in murine cutaneous and visceral leishmaniasis. Parasites & vectors . 2014; 7; 3. [PubMed: 24382098 ].
Gene Information
Gene Name
ribosomal protein L5
NCBI Gene ID
12982412
Protein Information
Protein Name
putative 60S ribosomal protein L5
NCBI Protein GI
XP_003722581
Protein pI
10.69
Protein Weight
32276.822
Protein Length
396
Protein Note
60S ribosomal protein L5; Provisional
Protein Sequence
>XP_003722581.1 putative 60S ribosomal protein L5 [Leishmania major strain Friedlin]
MPFVKVVKNKAYFKRFQVKYRRRREGKTDYHARRQMVLQDKTKFGSPKYRLVVRITNKDIIAQIVQAKIV
GDEVVMAAYAHELPAFGIEHGLTNYAAAYATGLLLARRTLAKLGIADKFQGAKEADGSYSAVRTKKDDEG
DDEERFPFKAILDVGLARTTTGARVFGVLKGAVDGGMAVPHRPNRFPGYNKEKSSLDAKVHRDRIFGKHV
ADYLKQVKEEASSNPDEKCVQFSKYMAAKVLPESIEGMYKKAHAAIRADPSKSLPKKAKKEGVAHKSYKT
KKLSGAEKRAAAKAKVAAIRERLGK
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
117600
PKKAK
265
270
MPFVKVVKNKAYFKRFQVKYRRRREGKTDYHARRQMVLQDKTKFGSPKYRLVVRITNKDIIAQIVQAKIVGDEVVMAAYAHELPAFGIEHGLTNYAAAYATGLLLARRTLAKLGIADKFQGAKEADGSYSAVRTKKDDEGDDEERFPFKAILDVGLARTTTGARVFGVLKGAVDGGMAVPHRPNRFPGYNKEKSSLDAKVHRDRIFGKHVADYLKQVKEEASSNPDEKCVQFSKYMAAKVLPESIEGMYKKAHAAIRADPSKSLPKKAKKEGVAHKSYKTKKLSGAEKRAAAKAKVAAIRERLGK