VIOLIN: Vaccine Investigation and Online Information Network

Rv1813c

General Information

Protegen ID

4395

Sequence Strain (Species/Organism)

Mycobacterium tuberculosis H37Rv

Taxonomy ID

83332

Other Database IDs

CDD:316353

Molecule Role

Protective antigen

Molecule Role Annotation

ID93/GLA-SE protects against TB and MDR-TB in animals.(Bertholet et al., 2010)

Related Vaccines(s)

ID93/GLA-SE

References

Bertholet et al., 2010: Bertholet S, Ireton GC, Ordway DJ, Windish HP, Pine SO, Kahn M, Phan T, Orme IM, Vedvick TS, Baldwin SL, Coler RN, Reed SG. A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis. Science translational medicine. 2010; 2(53); 53ra74. [PubMed: 20944089].

Gene Information

Gene Name

Rv1813c

Protein Information

Protein Name

hypothetical protein

NCBI Protein GI

NP_216329

Protein pI

10.16

Protein Weight

14879.86

Protein Length

224

Protein Note

Domain of unknown function (DUF4189); pfam13827

Protein Sequence

>NP_216329.1 hypothetical protein Rv1813c [Mycobacterium tuberculosis H37Rv]
MITNLRRRTAMAAAGLGAALGLGILLVPTVDAHLANGSMSEVMMSEIAGLPIPPIIHYGAIAYAPSGASG
KAWHQRTPARAEQVALEKCGDKTCKVVSRFTRCGAVAYNGSKYQGGTGLTRRAAEDDAVNRLEGGRIVNW
ACN

Vaxign Prediction

Localization(Probability)

Unknown
(Prob.=0.333)

Adhesin Probability

0.288

Trans-membrane Helices

Detailed Vaxign Results

Vaxign Results

Epitope Information

IEDB Linear Epitope