esxV
General Information
Protegen ID
4396
Sequence Strain (Species/Organism)
Mycobacterium tuberculosis H37Rv
Taxonomy ID
83332
Other Database IDs
CDD:310537
Molecule Role
Protective antigen
Molecule Role Annotation
ID93/GLA-SE protects against TB and MDR-TB in animals.(Bertholet et al. , 2010 )
Related Vaccines(s)
ID93/GLA-SE
References
Bertholet et al. , 2010: Bertholet S, Ireton GC, Ordway DJ, Windish HP, Pine SO, Kahn M, Phan T, Orme IM, Vedvick TS, Baldwin SL, Coler RN, Reed SG. A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis . Science translational medicine . 2010; 2(53); 53ra74. [PubMed: 20944089 ].
Gene Information
Gene Name
esxV
Protein Information
Protein Name
ESAT-6 like protein EsxV
NCBI Protein GI
NP_218136
Protein pI
4.62
Protein Weight
10489.63
Protein Length
170
Protein Note
Proteins of 100 residues with WXG; pfam06013
Protein Sequence
>NP_218136.1 ESAT-6 like protein EsxV [Mycobacterium tuberculosis H37Rv]
MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANA
HGQKVQAAGNNMAQTDSAVGSSWA
Vaxign Prediction
Localization(Probability)
Unknown (Prob.=0.25)
Adhesin Probability
0.790
Trans-membrane Helices
0
Detailed Vaxign Results
Vaxign Results
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
Starting position
Ending position
103170
FGDVDAHGAMIRAQA
7
22
120892
QKVQAAGNNMAQT
73
86
MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA