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esxV

General Information
Protegen ID 4396
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
Taxonomy ID 83332
Other Database IDs CDD:310537
Molecule Role Protective antigen
Molecule Role Annotation ID93/GLA-SE protects against TB and MDR-TB in animals.(Bertholet et al., 2010)
Related Vaccines(s) ID93/GLA-SE
References
Bertholet et al., 2010: Bertholet S, Ireton GC, Ordway DJ, Windish HP, Pine SO, Kahn M, Phan T, Orme IM, Vedvick TS, Baldwin SL, Coler RN, Reed SG. A defined tuberculosis vaccine candidate boosts BCG and protects against multidrug-resistant Mycobacterium tuberculosis. Science translational medicine. 2010; 2(53); 53ra74. [PubMed: 20944089].
Gene Information
Gene Name esxV
Protein Information
Protein Name ESAT-6 like protein EsxV
NCBI Protein GI NP_218136
Protein pI 4.62
Protein Weight 10489.63
Protein Length 170
Protein Note Proteins of 100 residues with WXG; pfam06013
Protein Sequence 
>NP_218136.1 ESAT-6 like protein EsxV [Mycobacterium tuberculosis H37Rv]
MTINYQFGDVDAHGAMIRAQAGSLEAEHQAIISDVLTASDFWGGAGSAACQGFITQLGRNFQVIYEQANA
HGQKVQAAGNNMAQTDSAVGSSWA
Vaxign Prediction
Localization(Probability) Unknown
(Prob.=0.25)
Adhesin Probability 0.790
Trans-membrane Helices 0
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope