VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (26)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


Ssb

General Information
Protegen ID 441
Sequence Strain (Species/Organism) Chlamydophila pneumoniae CWL029
VO ID VO_0010896
Taxonomy ID 115713
Molecule Role Protective antigen
Molecule Role Annotation Mice vaccinated with candidate gene ssb showed significant reduction of spleen chlamydial loads as compared to naïve, non-protected control mice (p ≤ 0.048). This resulted in the ability of ssb to mediate a modest, but significant level of protection in an inbred A/J mouse respiratory challenge model (Li et al., 2006).
Related Vaccines(s) C. pneumoniae DNA vaccine encoding Ssb
References
Li et al., 2006: Li D, Borovkov A, Vaglenov A, Wang C, Kim T, Gao D, Sykes KF, Kaltenboeck B. Mouse model of respiratory Chlamydia pneumoniae infection for a genomic screen of subunit vaccine candidates. Vaccine. 2006; 24(15); 2917-2927. [PubMed: 16434129].
Gene Information
Gene Name Ssb
NCBI Gene ID 894901
Genbank Accession AE001363
Locus Tag CPn0386
Gene Starting Position 434042
Gene Ending Position 434524
DNA Sequence 
>NC_000922.1:434042-434524 Chlamydophila pneumoniae CWL029 chromosome, complete genome
ATTAAAAAGGAACATCTTCACAGACATACTGCTGTTCTTGACCATAACCAGCATACATATCTTTATCTTT
AATAGCTTCTGCGTCCAGTGCTTCACCTTCAAACCCTACGGATACAGATTCATATCCCACTTGCTGATGA
TTGTCTTCTAAAGATGGAGAACGGCTGCCTTCATTGCGACCGAAAGGACTGAATTTCAAAGAATCTACAC
TAATCACTAAAGAAGATTGCGGTGAACCATCTTTGCTCATGTAACTCTCTACAGAGATATCGCCAGCAAC
AATGACTCCTGAGCCTTTCTTCAAGTAAGGAAGCATCTTATCATAGCGATTGTGCCAAATATTGCATTTG
CACCAAACAGTTTCATCTTTCATTCCAACTCGAGTCTTCACTCCCAGTCTCAGAGTGATCACACGTTTTC
CTTTGGAAGTCATTCGCTCTTCAGGATCTGCTCCAAGGTAACCAGCAAAATGCCCAAACATCA
Protein Information
Protein Name single-stranded DNA-binding protein
NCBI Protein GI 15618301
Protein Accession NP_224586
Protein pI 5.29
Protein Weight 16434.22
Protein Length 160
Protein Note binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA
Protein Sequence 
>NP_224586.1 single-stranded DNA-binding protein [Chlamydia pneumoniae CWL029]
MMFGHFAGYLGADPEERMTSKGKRVITLRLGVKTRVGMKDETVWCKCNIWHNRYDKMLPYLKKGSGVIVA
GDISVESYMSKDGSPQSSLVISVDSLKFSPFGRNEGSRSPSLEDNHQQVGYESVSVGFEGEALDAEAIKD
KDMYAGYGQEQQYVCEDVPF
Epitope Information
IEDB Linear Epitope