VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (28)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


MIC2

General Information
Protegen ID 459
Sequence Strain (Species/Organism) Eimeria tenella
VO ID VO_0011063
Taxonomy ID 5802
Other Database IDs CDD:115333
Molecule Role Protective antigen
Molecule Role Annotation Birds vaccinated with Eimeria tenella microneme recombinant gene (EtMIC2) and encoded protein developed protective immunity against infection by E. tenella as assessed by significantly increased body weight gain and decreased fecal oocyst shedding compared with non-vaccinated controls. Vaccination with the EtMIC2 gene also led to protective immunity against infection by E. acervulina, but not E. maxima (Ding et al., 2005).
Additional Molecule Role Protective antigen
Related Vaccines(s) E. tenella DNA vaccine EtMIC2
References
Ding et al., 2005: Ding X, Lillehoj HS, Dalloul RA, Min W, Sato T, Yasuda A, Lillehoj EP. In ovo vaccination with the Eimeria tenella EtMIC2 gene induces protective immunity against coccidiosis. Vaccine. 2005; 23(28); 3733-3740. [PubMed: 15882535].
Gene Information
Gene Name MIC2
Protein Information
Protein Name microneme 2
NCBI Protein GI 225579627
Protein pI 4.13
Protein Weight 32481.77
Protein Length 390
Protein Note Microneme protein Etmic-2; pfam06670
Protein Sequence
>ACN93990.1 microneme 2 [Eimeria tenella]
MARALSLVALGLLFSLPPSSAVRTRVPGEDSFSPESGVLSGTDAPERRPIVPGLVEGNCGRLTVRNGPSV
DETIKVTSAGWTKSERDFIVSLVADETRKVVQLRESEGASGASGPGPAPAEKPPSGQGSAEEAPKGEGGQ
EKPSVPLIAVRIHGSGGDKGESAPQSAVLLYGNDESEPTEVPLETAAGPTTPLMVLITQQNPKEVEVRVL
AWISTDATTGKGSWKENSVVVGSSLSGRDLTVNLGDCGPSSLRVYGSASADLVTVKEGMCEADDPELIAL
TRPHTSAASPLPAEEGDVAQDAQQSAGAQQEAEAQEVGEPQQEAAAAEQGSSAAESDTQQSS

Epitope Information
IEDB Linear Epitope