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OmpP2

General Information
Protegen ID 485
Sequence Strain (Species/Organism) Haemophilus influenzae 86-028NP
VO ID VO_0011084
Taxonomy ID 281310
Molecule Role Protective antigen
Molecule Role Annotation Rabbit antibody prepared against P2 from one strain was cross-reactive with P2 isolated from the other two heterologous strains by Western blot. This antibody passively protected infant rats against type b Haemophilus infection caused by the homologous organism, but not against challenge by a strain with the heterologous 36,500 mol wt P2 protein (Munson et al., 1983).
COG COG3203M, under M: Cell wall/membrane/envelope biogenesis
References
Munson et al., 1983: Munson RS Jr, Shenep JL, Barenkamp SJ, Granoff DM. Purification and comparison of outer membrane protein P2 from Haemophilus influenzae type b isolates. The Journal of clinical investigation. 1983; 72(2); 677-684. [PubMed: 6603479].
Gene Information
Gene Name OmpP2
NCBI Gene ID 3429565
Genbank Accession CP000057
Locus Tag NTHI0225
Gene Starting Position 216248
Gene Ending Position 217345
DNA Sequence 
>NC_007146.2:216248-217345 Haemophilus influenzae 86-028NP, complete genome
TATGAAAAAAACACTTGCAGCATTAATCGTTGGTGCATTCGCAGCTTCAGCAGCAAACGCAGCTGTTGTT
TATAACAACGAAGGGACTAACGTAGAATTAGGTGGTCGTTTAAGCATTATCGCAGAACAAAGTAATAGCA
CTATAAAGGATCAAAAACAGCAACACGGTGCATTACGCAATCAAAGTTCACGTTTCCACATTAAAGCAAC
TCATAACTTCGGTGATGGTTTCTATGCACAAGGTTATTTAGAAACTCGTTTAGTTTCAGCTCAATCTGGA
ACCGAGTCAGATAACTTCGGTCATATTATAACCAAATATGCTTATGTCACTTTAGGAAATAAAGCATTGG
GTGAAGTAAAACTTGGTCGTGCGAAAACTATTGCTGATGGCATAACAAGCGCAGAAGATAAAGAATATGG
TGTTCTCAACAATAGCAAATATATTCCTACTAATGGTAATACCGTTGGCTACACTTTTAAAGGTATCGAT
GGTTTAGTATTAGGTGCTAATTATTTATTAGCACAAGAGCGTCATAAGTATACTACTGCTGCTGGTACTC
GTGCTGTTACTGTTGCAGGAGAAGTTTATCCACAAAAAATCAGCAATGGCGTTCAGGTTGGTGCAAAATA
TGATGCAAACAACATTATTGCAGGTATTGCTTATGGTCGTACAAATTATAGAGAAGATATTGTTGACCCA
GATTTAGGTAAAAAACAACAAGTAAACGGTGCGCTTTCAACTTTAGGCTATCGTTTTAGTGATTTAGGCT
TATTAGTGTCTCTAGATAGTGGCTATGCAAAAACTAAAAACTATAAAGATAAACACGAAAAAAGCTATTT
CGTATCTCCAGGTTTCCAATATGAATTAATGGAAGATACTAATGTCTATGGCAACTTCAAATATGAACGC
GATTCTGTAGATCAAGGTAAAAAAACACGTGAACAAGCAGTGTTATTCGGTGTAGATCATAAACTTCACA
AACAAGTATTAACCTATATTGAAGGTGCTTACGCTAGAACTAGAACAACTGAGCAAGCTAAAGGCGTAAA
AACTGAAAAAGAAAAATCAGTGGGTGTAGGTTTACGCGTTTACTTCTA
Protein Information
Protein Name outer membrane protein P2
NCBI Protein GI 68248747
Protein Accession YP_247859
Protein pI 9.63
Protein Weight 37152.68
Protein Length 365
Protein Note Similar to: HI0139, OP27_HAEIN
Protein Sequence 
>YP_247859.1 outer membrane protein P2 [Haemophilus influenzae 86-028NP]
MKKTLAALIVGAFAASAANAAVVYNNEGTNVELGGRLSIIAEQSNSTIKDQKQQHGALRNQSSRFHIKAT
HNFGDGFYAQGYLETRLVSAQSGTESDNFGHIITKYAYVTLGNKALGEVKLGRAKTIADGITSAEDKEYG
VLNNSKYIPTNGNTVGYTFKGIDGLVLGANYLLAQERHKYTTAAGTRAVTVAGEVYPQKISNGVQVGAKY
DANNIIAGIAYGRTNYREDIVDPDLGKKQQVNGALSTLGYRFSDLGLLVSLDSGYAKTKNYKDKHEKSYF
VSPGFQYELMEDTNVYGNFKYERDSVDQGKKTREQAVLFGVDHKLHKQVLTYIEGAYARTRTTEQAKGVK
TEKEKSVGVGLRVYF
Epitope Information
IEDB Linear Epitope