VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (26)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


HA

General Information
Protegen ID 549
Sequence Strain (Species/Organism) Influenza A virus (A/turkey/Ireland/1378/1983(H5N8))
VO ID VO_0011141
Taxonomy ID 380285
Other Database IDs CDD:278910
Molecule Role Protective antigen
Molecule Role Annotation All specific-pathogen-free chickens immunized with (vFP89) expressing the native hemagglutinin (HA) gene from H5N8 A/turkey/ Ireland/1378/83 were clinically protected from HPAI challenge (Bublot et al., 2010).
Related Vaccines(s) FP-AI-H5(H5N1) , Influenza virus DNA vaccine pCMVH5HA , Influenza virus DNA vaccine pβactinH7HA , vFP89-H5 , vFP89-HA (H5N1 HPAI virus)
References
Bublot et al., 2010: Bublot M, Manvell RJ, Shell W, Brown IH. High level of protection induced by two fowlpox vector vaccines against a highly pathogenic avian influenza H5N1 challenge in specific-pathogen-free chickens. Avian diseases. 2010; 54(1 Suppl); 257-261. [PubMed: 20521642].
Gene Information
Gene Name HA
Protein Information
Protein Name hemagglutinin
NCBI Protein GI 115279333
Protein pI 7.46
Protein Weight 62067.27
Protein Length 657
Protein Note Haemagglutinin; pfam00509
Protein Sequence 
>ABI85117.1 hemagglutinin [Influenza A virus (A/turkey/Ireland/1378/1983(H5N8))]
MEKIVLLFAIVSLVRSDQICIGYHANNSTKQVDTIMEKNVTVTHAQDILEKTHNGKLCSLNGVKPLILRD
CSVAGWLLGNPMCDEFLNVPEWSYIVEKDNPVNGLCYPGDFNDYEELKHLLSCTKHFEKIRIIPRDSWPN
HEASLGVSSACPYNGRSSFFRNVVWLIKKNNAYPTIKRSYSNTNKEDLLILWGIHHPNDAAEQTKLYQNP
TTYVSVGTSTLNQRSIPKIATRPELNGQSGRMEFFWTILKPSDTINFESNGNFIAPEYAYKIVKKGDSAI
MKSGLEYGNCNTKCQTPIGAINSSMPLHNIHPLTIGECPKYVKSDRLVLATGLRNTPQRKRKKRGLFGAI
AGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQRAIDGITNKVNSIIDKMNTQFEAVGKEFNNLERR
IENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDANVKSLYDKVRLQLKDNARELGNGCFEFYHKCDN
ECMESIRNGTYNYPQYSEEARLNREEISGVKLESMGIYQILSIYSTVASSLALAIMIAGLSFWMCSNGSL
QCRICI
Vaxign Prediction
Localization(Probability)
(Prob.=0)
Adhesin Probability 0.272
Trans-membrane Helices 1
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope