VIOLIN: Vaccine Investigation and Online Information Network

NS1

General Information

Protegen ID

556

Sequence Strain (Species/Organism)

Japanese encephalitis virus

VO ID

VO_0011147

Taxonomy ID

11072

Other Database IDs

CDD:279316

Molecule Role

Protective antigen

Molecule Role Annotation

Balb/c mice and swine vaccinated with TK(-)/gG(-)/NS1(+) expressing NS1 protein of JEV could confer protective immunity against lethal challenge of the virulent PRV Ea strain and develop a good humoral and cellular immune response against JEV (Xu et al., 2004).

Related Vaccines(s)

Japanese encephalitis virus DNA vaccine encoding NS1 (pUSK-NS1) , Japanese encephalitis virus DNA Vaccine P-JEV , NYVAC-JEV- prM/E/ NS1

References

Xu et al., 2004: Xu G, Xu X, Li Z, He Q, Wu B, Sun S, Chen H. Construction of recombinant pseudorabies virus expressing NS1 protein of Japanese encephalitis (SA14-14-2) virus and its safety and immunogenicity. Vaccine. 2004; 22(15-16); 1846-1853. [PubMed: 15121294].

Gene Information

Gene Name

NS1

Protein Information

Protein Name

NS1 protein

NCBI Protein GI

18418672

Protein pI

8.12

Protein Weight

16884.93

Protein Length

218

Protein Note

isolated from porcine sera

Protein Sequence

>AAL68990.1 NS1 protein, partial [Japanese encephalitis virus]
ELIIPHTIAGPRSKHNRREGYKTQNQGPWDENGIVLDFDYCPGTKVTITEDCGKRGPSIRTTTDSGKLIT
DWCCRSCSLPPLRFRTENGCWYGMEIRPVRHDETTLVRSQVDAFNGEMIDPFQLGLLVMFLATQEVLRKR
WTARLTIPAVL

Epitope Information

IEDB Linear Epitope