VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (28)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


SERA-5

General Information
Protegen ID 626
Sequence Strain (Species/Organism) Plasmodium falciparum
VO ID VO_0011210
Taxonomy ID 5833
Other Database IDs CDD:185641
Molecule Role Protective antigen
Molecule Role Annotation Researchers constructed a new recombinant molecule of SERA5, namely SE36. Vaccination of Squirrel monkeys with SE36 protein and aluminium hydroxyl gel (SE36/AHG) conferred protection against high parasitemia and boosted serum anti-SE36 IgG after P. falciparum parasite challenge (Horii et al., 2010).
Related Vaccines(s) P. falciparum Subunit SE36 Protein Vaccine
References
Horii et al., 2010: Horii T, Shirai H, Jie L, Ishii KJ, Palacpac NQ, Tougan T, Hato M, Ohta N, Bobogare A, Arakaki N, Matsumoto Y, Namazue J, Ishikawa T, Ueda S, Takahashi M. Evidences of Protection Against Blood-stage Infection of Plasmodium falciparum by the Novel Protein Vaccine SE36. Parasitology international. 2010; ; . [PubMed: 20493274].
Gene Information
Gene Name SERA-5
NCBI Gene ID 812668
Protein Information
Protein Name serine repeat antigen 5
NCBI Protein GI 238629807
3D structure: PDB ID 3CH2
Protein pI 6.14
Protein Weight 28688.67
Protein Length 362
Protein Note Serine-repeat antigen protein; Provisional
Protein Sequence
>ACR49652.1 serine repeat antigen 5, partial [Plasmodium falciparum]
TGGGQAGNTGGGQAGNTGGGQAGNTVGDQAGSTGGSPQGSTGASQPGSSEPSNPVSSGHSVSTVSVSQTS
TSSEKQDTIQVKSALLKDYMGLKVTGPCNENFIMFLVPHIYIDVDTEDTNIELRTTLKKTNNAISFESNS
GSLEKKKYVKLPSNGTTGEQGSSTGTVRGDTEPISDSSSSSSSSSSSSSSSSSSSSSSSESLPANGPDSP
TVKPPRNLQNICETGKNFKLVVYIKENTLILKWKVYGETKDTTENNKVDVRKYLINEKETPFTNILIHAY
KEHNEQT

Epitope Information
IEDB Linear Epitope