VIOLIN: Vaccine Investigation and Online Information Network

GII

General Information

Protegen ID

665

Sequence Strain (Species/Organism)

Suid herpesvirus 1

VO ID

VO_0011249

Taxonomy ID

10345

Other Database IDs

CDD:223014

Molecule Role

Protective antigen

Molecule Role Annotation

A NYVAC vaccinia vector containing genes for pseudorables virus glycoproteins gII and gp50 was administered to pigs to determine if it would have a greater protective effect than a vector containing the gene for gp50 alone. Both NYVAC vectors protected pigs similarly from virulent pseudorabies virus challenge (Brockmeier and Mengeling, 1996).

Related Vaccines(s)

NYVAC-PRV- gII/ gp50 , Pseudorabies recombinant vector vaccine encoding gp50 and gII protein

References

Brockmeier and Mengeling, 1996: Brockmeier SL, Mengeling WL. Comparison of the protective response induced by NYVAC vaccinia recombinants expressing either gp50 or gII and gp50 of pseudorabies virus. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 1996; 60(4); 315-317. [PubMed: 8904669].

Gene Information

Gene Name

GII

Protein Information

Protein Name

glycoprotein gII

NCBI Protein GI

1335775

Protein pI

11.38

Protein Weight

14546.78

Protein Length

200

Protein Note

glycoprotein BALF4; Provisional

Protein Sequence

>AAB26946.1 glycoprotein gII, partial [Suid alphaherpesvirus 1]
PFGALAIGLLVLAGLVAAFLAYRHISRLRRNPMKALYPVTTKALKEDGVEEGDVDEAKLDQARDMIRYMS
IVSALEQQEHRRARRTAGPRSWPAGSGRWLRAAGTTSASRARTPTPCSPLPRETIKMRLFGNT

Epitope Information

IEDB Linear Epitope