VIOLIN: Vaccine Investigation and Online Information Network

GI

General Information

Protegen ID

668

Sequence Strain (Species/Organism)

Suid herpesvirus 1

VO ID

VO_0011251

Taxonomy ID

10345

Other Database IDs

CDD:177577
CDD:165547

Molecule Role

Protective antigen

Molecule Role Annotation

Vaccination of mice with fusion proteins containing the N terminus of gI from Suid herpesvirus 1 are able to confer protection to mice against a lethal challenge of PRV (Fuchs et al., 1990).

Related Vaccines(s)

Pseudorabies Subunit gI Protein Vaccine

References

Fuchs et al., 1990: Fuchs W, Rziha HJ, LukÃ cs N, Braunschweiger I, Visser N, LÃ¼tticken D, Schreurs CS, Thiel HJ, Mettenleiter TC. Pseudorabies virus glycoprotein gI: in vitro and in vivo analysis of immunorelevant epitopes. The Journal of general virology. 1990; 71 ( Pt 5); 1141-1151. [PubMed: 1693164].

Gene Information

Gene Name

Protein Information

Protein Name

envelope glycoprotein gI

NCBI Protein GI

255957222

Protein pI

9.1

Protein Weight

35302.37

Protein Length

440

Protein Note

envelope glycoprotein I; Provisional

Protein Sequence

>ACU43467.1 envelope glycoprotein gI, partial [Suid alphaherpesvirus 1]
RDVTRLPAGLLLAALTLAALTPRVGGVLFRGAGVSVHVAGSAVLVPGDAPNLTIDGTLLFLEGPSPSNYS
GRVELLRLDPKRACYTREYAAEYDLCPRVHHEAFRGCLRKREPLARRASAAVEARRLLFVSRPAPPDAGS
YVLRVRVNGTTDLFVLTALVPPRGRPHHPTPSSADECRPVVGSWHDSLRAVDPAEDAVFTTQPPPEPEPP
TTPAPPRGTGATPEPRSDEEEEDEEGATTAMTPAPGTLDANGTMVLNASVVSRVLLAAANATAGARGPGK
IAMVLGPTIVVLLIFLGGVACAARRCARNRIYRPRPGRGPAVHAPPPRRPPPSPVAGAPVPQPKMTLAEL
RQKLATIAEEQ

Epitope Information

IEDB Linear Epitope