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A21L

General Information
Protegen ID 68
Sequence Strain (Species/Organism) Vaccinia virus
VO ID VO_0012363
Taxonomy ID 10245
Molecule Role Protective antigen
Related Vaccines(s) LC16m8
References  
Gene Information
Gene Name A21L
NCBI Gene ID 3707670
Genbank Accession AY603355
Locus Tag VACWR140
Gene Starting Position 127904
Gene Ending Position 128257
DNA Sequence
>NC_006998.1:127904-128257 Vaccinia virus, complete genome
TTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCT
ATCTTTATCACAATATAGTGTATCGACATCTTTATTATTATTGACCTCGTTTATCTTGGAACATGGAATG
GGAACATTTTTGTTATCAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTC
TATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCGCGTCTCAT
TTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTT
ATCA

Protein Information
Protein Name IMV membrane protein
NCBI Protein GI 66275937
Protein Accession YP_233022
Protein pI 8.71
Protein Weight 12850.65
Protein Length 117
Protein Note IMV membrane protein; similar to vaccinia virus strain Copenhagen A21L; The poxviridae are enveloped unsegmented dsDNA viruses; unlike many dsDNA viruses that replicate in the host nucleus poxviruses encode their own replication machinery and therefore replicate in the cytoplasm; viral genes are expressed in a bi-phasic manner with early genes encoding non-structural proteins involved in genome replication and late genes encoding the viral structural proteins
Protein Sequence
>YP_233022.1 Membrane protein [Vaccinia virus]
MITLFLILCYFILIFNIIVPAISEKMRRERAAYVNYKRLNKNFICVDDRLFSYNFTTSGIKAKVAVDNKN
VPIPCSKINEVNNNKDVDTLYCDKDRDDIPGFARSCYRAYSDLFFTT

Vaxign Prediction
Localization(Probability)
(Prob.=0)
Adhesin Probability 0.356
Trans-membrane Helices 1
Detailed Vaxign Results Vaxign Results
Epitope Information
IEDB Linear Epitope