ctxB
General Information
Protegen ID
731
VO ID
VO_0011270
Taxonomy ID
127906
Other Database IDs
CDD:279687
Molecule Role
Protective antigen
Molecule Role Annotation
The immune sera elicited by CTB DNA vaccine were functional and protective against V. cholerae O1 infection in mice (Xu et al. , 2009 ).
Related Vaccines(s)
V. cholerae CTB DNA Vaccine
References
Xu et al. , 2009: Xu G, Wang S, Zhuang L, Hackett A, Gu L, Zhang L, Zhang C, Wang H, Huang Z, Lu S. Intramuscular delivery of a cholera DNA vaccine primes both systemic and mucosal protective antibody responses against cholera. Vaccine . 2009; 27(29); 3821-3830. [PubMed: 19443090 ].
Gene Information
Gene Name
ctxB
Protein Information
Protein Name
cholera toxin B
NCBI Protein GI
110264635
Protein pI
8.47
Protein Weight
11386.27
Protein Length
165
Protein Note
Heat-labile enterotoxin beta chain; pfam01376
Protein Sequence
>ABG56901.1 cholera toxin B, partial [Vibrio cholerae O1]
MIKLKFGVFFTVLLSSAYAHGTPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQ
VEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVE
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
MIKLKFGVFFTVLLSSAYAHGTPQNITDLCAEYHNTQIHTLNDKIFSYTESLAGKREMAIITFKNGATFQVEVPGSQHIDSQKKAIERMKDTLRIAYLTEAKVE
