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DbpA

General Information
Protegen ID 841
Sequence Strain (Species/Organism) Borrelia burgdorferi 297
VO ID VO_0012387
Taxonomy ID 521009
Molecule Role Protective antigen
Molecule Role Annotation Mice immunized with recombinant DbpA protein are protected against challenge with Borrelia burgdorferi (Hanson et al., 2000).
Related Vaccines(s) B. burgdorferi DbpA and OspA Protein Vaccine , B. burgdorferi DbpA Protein Vaccine
References
Hanson et al., 2000: Hanson MS, Patel NK, Cassatt DR, Ulbrandt ND. Evidence for vaccine synergy between Borrelia burgdorferi decorin binding protein A and outer surface protein A in the mouse model of lyme borreliosis. Infection and immunity. 2000; 68(11); 6457-6460. [PubMed: 11035759].
Gene Information
Gene Name DbpA
NCBI Gene ID 8319341
Genbank Accession U75866
Locus Tag Bbu297_A24
Plasmid No 297_lp54
Gene Starting Position 13807
Gene Ending Position 14370
DNA Sequence 
>NC_013128.1:13807-14370 Borrelia burgdorferi 297 plasmid 297_lp54, complete sequence
ATTACGATTTAGCAGTGCTGTCTTCGGTATTTTTTTTCTTTAAGGTGTCTTGGTTTTTCTTGTGAACCCT
TTGTAATTTTTCTCTCATTTTTTTTGCAATTTCAAGCACTCCTTGAGCTGTAGTTGGAGGATTCTCTTCA
GCTGCCATTGAGACTGTTTTTGTCATCTCTTGTATTCCCAATTCTTGTAATGGTTTTGAGACTTCAAACA
TTAAATCATACATTGCTGAGAATTCACCACTACTTCCAGTTTCTTTAAGTTTAGTAGCTTCCTCTTCTAT
TGCTATTACGAATTTTTCCGCTACTGTAGTAGCTCGCACTTTTGCTTCAAGTATGAATGGATTTTCTGAT
ACCCCACTACCCGTTTTTTTATCTTTAAAGGCATCAAAATTTACACCCATAGAAGCAGCCTTTTTTTTAA
TTGCATCTATTTCATCTACAATGGCTTTAGCTGATGATTCTAATTTGATTTTTGTTGCTCCTGTTAGTCC
ACATGATATAAGTAGGTTAACAAGTATAGTTAGTTTAAGTAAATTGTTAAAAGTTTTATTATTACATTTA
ATCA
Protein Information
Protein Name decorin binding protein A
NCBI Protein GI 256041910
Protein Accession YP_003110629
Protein pI 9.68
Protein Weight 19412.03
Protein Length 187
Protein Note identified by match to protein family HMM PF02352
Protein Sequence 
>YP_003110629.1 decorin binding protein A (plasmid) [Borreliella burgdorferi 297]
MIKCNNKTFNNLLKLTILVNLLISCGLTGATKIKLESSAKAIVDEIDAIKKKAASMGVNFDAFKDKKTGS
GVSENPFILEAKVRATTVAEKFVIAIEEEATKLKETGSSGEFSAMYDLMFEVSKPLQELGIQEMTKTVSM
AAEENPPTTAQGVLEIAKKMREKLQRVHKKNQDTLKKKNTEDSTAKS
Epitope Information
IEDB Linear Epitope