VIOLIN: Vaccine Investigation and Online Information Network

fbaA

General Information

Protegen ID

853

Sequence Strain (Species/Organism)

Streptococcus pyogenes SSI-9

VO ID

VO_0012396

Taxonomy ID

1314

Other Database IDs

CDD:273479
CDD:320995
CDD:273478

Molecule Role

Protective antigen

Molecule Role Annotation

Mice immunized with FbpA were protected from challenge with group A streptococcus (Ma et al., 2009).

Related Vaccines(s)

S. pyogenes FbaA Protein Vaccine

References

Ma et al., 2009: Ma CQ, Li CH, Wang XR, Zeng RH, Yin XL, Feng HD, Wei L. Similar ability of FbaA with M protein to elicit protective immunity against group A streptococcus challenge in mice. Cellular & molecular immunology. 2009; 6(1); 73-77. [PubMed: 19254483].

Gene Information

Gene Name

fbaA

Protein Information

Protein Name

fibronectin-binding protein

NCBI Protein GI

14915682

Protein pI

4.73

Protein Weight

36233.27

Protein Length

427

Protein Note

Gram-positive signal peptide, YSIRK family; TIGR01168

Protein Sequence

>BAB62098.1 fibronectin-binding protein [Streptococcus pyogenes]
MRRAENNKHSRYSIRKLSVGVTSIAIASLFLGKVAYAVDGIPPISLTQKTTATTSENWHHIDKDGLIPLG
ISLEAAKEEFKKEVEESRLSEAQKETYKQKIKTAPDKDKLLFTYHSEYMTAVKDLPASTESTTQPVEAPV
QETQASASDSMVTGDSTSVTTDSPEETPSSESPVAPALSEAPAQPAESEEPSVAASSEETPSPSTPAAPS
TPAAPETPEEPAAPSQPAESEESSVAATTSPSPSTPAESETQTPPAVTKDSDKPSSAAEKPAASSLVSEQ
TVQQPTSKRSSDKKEEQEQSYSPNRSLSRQVRAHESGKYLPSTGEKAQPLFIATMTLMSLFGSLLVTKRQ
KETKK

Epitope Information

IEDB Linear Epitope