VIOLIN Logo
VO Banner
Search: for Help
Protegen Home
Introduction
Statistics
News and Updates
Protegen Query
Protegen BLAST
Selected Bacteria
Brucella spp. (26)
B. anthracis (14)
E. coli (40)
M. tuberculosis (26)
N. meningitidis (18)
Selected Viruses
Ebola virus (19)
HIV (41)
Influenza virus (50)
Selected Parasites
Plasmodium (47)
Data Submission
Data Exchange
Data Download
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo


Sip

General Information
Protegen ID 859
Sequence Strain (Species/Organism) Streptococcus agalactiae A909
VO ID VO_0012402
Taxonomy ID 205921
Other Database IDs CDD:212030
CDD:331378
Molecule Role Protective antigen
Molecule Role Annotation Immunization with the recombinant Sip protein efficiently protected CD-1 mice against deadly challenges with six GBS strains of serotypes Ia/c, Ib, II/R, III, V, and VI (Brodeur et al., 2000).
Related Vaccines(s) S. agalactiae Sip Protein Vaccine
References
Brodeur et al., 2000: Brodeur BR, Boyer M, Charlebois I, Hamel J, Couture F, Rioux CR, Martin D. Identification of group B streptococcal Sip protein, which elicits cross-protective immunity. Infection and immunity. 2000; 68(10); 5610-5618. [PubMed: 10992461].
Gene Information
Gene Name Sip
NCBI Gene ID 3685788
Genbank Accession CP000114
Locus Tag SAK_0065
Gene Starting Position 47330
Gene Ending Position 48634
DNA Sequence 
>NC_007432.1:47330-48634 Streptococcus agalactiae A909, complete genome
AATGAAAATGAATAAAAAGGTACTATTGACATCGACAATGGCAGCTTCGCTATTATCAGTCGCAAGTGTT
CAAGCACAAGAAACAGATACGACGTGGACAGCACGTACTGTTTCAGAGGTAAAGGCTGATTTGGTAAAGC
AAGACAATAAATCATCATATACTGTGAAATATGGTGATACACTAAGCGTTATTTCAGAAGCAATGTCAAT
TGATATGAATGTCTTAGCAAAAATTAATAACATTGCAGATATCAATCTTATTTATCCTGAGACAACACTG
ACAGTAACTTACGATCAGAAGAGTCATACTGCTACTTCAATGAAAATAGAAACACCAGCAACAAATGCTG
CTGGTCAAACAACAGCTACTGTCGATTTGAAAACCAATCAAGTTTCTGTTGCAGACCAAAAAGTTTCTCT
CAATACAATTTCGGAAGGTATGACACCAGAAGCAGCAACAACGATTGTTTCGCCAATGAAGACATATTCT
TCTGCGCCAGCTTTGAAATCAAAAGAAGTATTAGCACAAGGGCAAGCTGTTAGTCAAGCAGCAGCTAATG
AACAGGTATCACCAGCTCCTGTGAAGTCGATTACTTCAGAAGTTCCAGCAGCTAAAGAGGAAGTTAAACC
AACTCAGACGTCAGTCAGTCAGTCAACAACAGTATCACCAGCTTCTGTTGCCGCTGAAACACCAGCTCCA
GTAGCTAAAGTAGCACCGGTAAGAACTGTAGCAGCCCCTAGAGTGGCAAGTGTTAAAGTAGTCACTCCTA
AAGTAGAAACTGGTGCATCACCAGAGCATGTATCAGCTCCAGCAGTTCCTGTGACTACGACTTCAACAGC
TACAGACAGTAAGTTACAAGCGACTGAAGTTAAGAGCGTTCCGGTAGCACAAAAAGCTCCAACAGCAACA
CCGGTAGCACAACCAGCTTCAACAACAAATGCAGTAGCTGCACATCCTGAAAATGCAAGGCTCCAACCTC
ATGTTGCAGCTTATAAAGAAAAAGTAGCGTCAACTTATGGAGTTAATGAATTCAGTACATACCGTGCGGG
AGATCCAGGTGATCATGGTAAAGGTTTAGCAGTTGACTTTATTGTAGGTAAAAACCAAGCACTTGGTAAT
GAAGTTGCACAGTACTCTACACAAAATATGGCAGCAAATAACATTTCATATGTTATCTGGCAACAAAAGT
TTTACTCAAATACAAATAGTATTTATGGACCTGCTAATACTTGGAATGCAATGCCAGATCGTGGTGGCGT
TACTGCCAACCACTATGACCACGTTCACGTATCATTTAACAAATA
Protein Information
Protein Name group B streptococcal surface immunogenic protein
NCBI Protein GI 76788047
Protein Accession YP_328758
Protein pI 8.59
Protein Weight 40547.64
Protein Length 434
Protein Note Lysine Motif is a small domain involved in binding peptidoglycan; cd00118
Protein Sequence 
>YP_328758.1 group B streptococcal surface immunogenic protein [Streptococcus agalactiae A909]
MKMNKKVLLTSTMAASLLSVASVQAQETDTTWTARTVSEVKADLVKQDNKSSYTVKYGDTLSVISEAMSI
DMNVLAKINNIADINLIYPETTLTVTYDQKSHTATSMKIETPATNAAGQTTATVDLKTNQVSVADQKVSL
NTISEGMTPEAATTIVSPMKTYSSAPALKSKEVLAQGQAVSQAAANEQVSPAPVKSITSEVPAAKEEVKP
TQTSVSQSTTVSPASVAAETPAPVAKVAPVRTVAAPRVASVKVVTPKVETGASPEHVSAPAVPVTTTSTA
TDSKLQATEVKSVPVAQKAPTATPVAQPASTTNAVAAHPENARLQPHVAAYKEKVASTYGVNEFSTYRAG
DPGDHGKGLAVDFIVGKNQALGNEVAQYSTQNMAANNISYVIWQQKFYSNTNSIYGPANTWNAMPDRGGV
TANHYDHVHVSFNK
Epitope Information
IEDB Linear Epitope