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BipA

General Information
Protegen ID 869
Sequence Strain (Species/Organism) Streptococcus agalactiae
Taxonomy ID 1311
Other Database IDs CDD:310807
CDD:114603
CDD:307064
Molecule Role Protective antigen
Molecule Role Annotation Mice immunized with BibA were protected against challenge by a GBS strain with high levels of surface exposure of the antigen (Santi et al., 2009).
Related Vaccines(s) S. agalactiae BipA Protein Vaccine
References
Santi et al., 2009: Santi I, Maione D, Galeotti CL, Grandi G, Telford JL, Soriani M. BibA induces opsonizing antibodies conferring in vivo protection against group B Streptococcus. The Journal of infectious diseases. 2009; 200(4); 564-570. [PubMed: 19586417].
Gene Information
Gene Name BipA
Protein Information
Protein Name BibA
NCBI Protein GI 255961211
Protein pI 9.74
Protein Weight 59842.07
Protein Length 648
Protein Note MucBP domain; pfam06458
Protein Sequence 
>ACU44481.1 BibA [Streptococcus agalactiae]
MNNNEKKVKYFLRKTAYGLASMSAAFIVCSGIVNTPTVSADSPDTLKVEKLGKLKDVKSVHELTPISIPN
ELKGAKEQALSSIISHPNITNSEVDKLASDYSFRINTSNDVNDVKRLLNEFYNAVARKQLDTNSADYRSK
IDNISTTGLAIALEAKEIYEANKSILPHRYKDSVGTYVNSFEERRSPGKFNIWNGQEGFNAAQKLLEDVK
KLLLELQNLTKNNKPNIQVPKQAPTEAAKPALSPEALTRLTTWYNQAKDLLKDDQVKDKYVDILSVQKAV
DQAYDHVEEGKFITTDQANQLANKLRDALQSLELKDKKVAKPVAKGTYDVKYVDTEGKEVAKSRHFEGEE
GAAFVTSAKEVAGYKLVRTEGAVSNVFTAGAQVRTYVYEKVAKPVAKGTYDVKYVDTEGKEVAKSRHFEG
EEGAAFVTSAKEVAGYKLVRTEGAVSNVFTAGAQVRTYVYEKVKPEVKPDVKPEAKPEAKPEVKPDVKPE
AKPEAKPEVKSDVKPEAKPEAKPEAKPEVKPDVKPEAKPEAKPATKKSVNTSGNLVAKKAIENKKYSKKL
PSTGEAASPLLAIVSLIVMLSAGLITIVLKHKKN
Epitope Information
IEDB Linear Epitope