VIOLIN: Vaccine Investigation and Online Information Network

ompH

General Information

Protegen ID

943

Sequence Strain (Species/Organism)

Pasteurella multocida strain X-73

Taxonomy ID

747

Other Database IDs

CDD:225744
CDD:238208

Molecule Role

Protective antigen

Molecule Role Annotation

rOmpH was used in a mice protection study. Mice immunized and challenged intraperitoneally resulted 100% protection against P. multocida whilst mice immunized subcutaneously and challenged intraperitoneally only resulted 80% protection (Tan et al., 2010).

Related Vaccines(s)

P. multocida rOmpH Vaccine

References

Tan et al., 2010: Tan HY, Nagoor NH, Sekaran SD. Cloning, expression and protective capacity of 37 kDa outer membrane protein gene (ompH) of Pasteurella multocida serotype B:2. Tropical biomedicine. 2010; 27(3); 430-441. [PubMed: 21399583].

Gene Information

Gene Name

ompH

NCBI Nucleotide GI

2745957

DNA Sequence

>gi|2745957|gb|U50907.1|PMU50907 Pasteurella multocida strain X-73 outer membrane protein (ompH) gene, complete cds
AAATATAAATAAAATTTGGGTGAAGTGAGAAATAGAGGCATTTACCCGATGTTTTTATCTTTGATTTATA
CTATTTTTGTTTTTAAATCAATGTGTTATGTTTTAAAAGAAAAGTTCTAAAGGAAATAAAATTTTTAATA
AATGTGATCTTTTTAACACTTTTTTAACCCTGAAAAAACCGCTGATTTTTTGTAACATGTTGTTTTTAAA
GGATAAGGTAAAAAAAAAGACAAACCTATTTTGTTTTGACAAGAAAACGGAGCTTTGCTATCTTGCATTT
GCAAAAATGTGCAGACGACTTATCGTCTGTTAGTCGATTTTAGGTTGATTGAGTGATTGGCAACAATCAT
TTAATCGAATTATAAAACTCCAAAAACAAGGTAGTGATACTATGAAAAAGACAATCGTAGCATTAGCAGT
CGCAGCAGTAGCAGCAACTTCAGCAAACGCAGCAACAGTTTACAATCAAGACGGTACCAAAGTTGATGTA
AACGGTTCTTTACGTTTAATCCTTAAAAAAGAAAAAAATGAGCGCGGTGATTTAGTGGATAACGGTTCAC
GCGTTTCATTCAAAGCATCTCATGATTTAGGCGAAGGCTTAAGCGCATTAGCTTATACAGAACTTCGTTT
TAGTAAAAATGTACCCGTGCAAGTAAAAGACCAACAAGGTGAAGTAGTACGTGAGTATGAGGTTGAGAAA
CTTGGTAACAATGTTCACGTAAAACGTCTTTATGCGGGTTTCGCGTATGAAGGTTTAGGTACATTAACAT
TCGGTAACCAATTAACTATCGGTGATGATGTTGGTCTATCTGACTATACCTATTTCAACAGTGGTATTAA
TAACCTCCTTTCTAGCGGTGAAAAAGCAATTAACTTTAAATCTGCAGAATTCAATGGTTTCACATTTGGT
GGTGCGTATGTCTTCTCTGCTGATGCTGACAAACAAGCATTACGTGATGGTCGCGGTTTCGTTGTAGCAG
GTTTATACAACAGAAAAATGGGTGATGTTGGTTTTGCATTCGAAGCCGGTTATAGCCAAAAATATGTGAA
ACAAGAAGTTGAACAGAATCCGCCAGCAGCACAAAAAGTGTTTAAAGATGAAAAAGAGAAAGCTTTCATG
GTGGGTGCTGAGTTATCATATGCTGGTTTAGCGCTTGGTGTTGACTACGCACAATCTAAAGTGACTAACG
TAGATGGTAAAAAACGTGCTCTTGAAGTGGGTTTAAATTATGACCTTAACGACAGAGCGAAAGTTTACAC
AGACTTCATCTGGGAAAAAGAAGGTCCTAAAGGTGATGTTACAAGAAACCGTACTGTCGCTGTAGGTTTT
GGTTACAAACTTCACAAACAAGTGGAAACTTTTGTTGAAGCAGCTTGGGGTAGAGAGAAAGACTCTGATG
GTGTAACAACAAAAAACAACGTAGTAGGTACAGGTTTACGCGTACACTTCTAATTTTTGTTAGAATCTGA
AAAAAGCCAGTGTTAAACACTGGCTTTTTATTGGGTTTTATTTGTTTTACTTACAATAAATTAGGATTTT
GAAAGTCGTTACGCGGTCATCTTTCTCAAAATAATACATATCAATATGTTGCAAGGAATGGATC

Protein Information

Protein Name

outer membrane protein

NCBI Protein GI

2745958

Protein Accession

AAC02243.1

Protein pI

8.3

Protein Weight

35024.16

Protein Length

419

Protein Note

OmpH

Protein Sequence

>AAC02243.1 outer membrane protein [Pasteurella multocida]
MKKTIVALAVAAVAATSANAATVYNQDGTKVDVNGSLRLILKKEKNERGDLVDNGSRVSFKASHDLGEGL
SALAYTELRFSKNVPVQVKDQQGEVVREYEVEKLGNNVHVKRLYAGFAYEGLGTLTFGNQLTIGDDVGLS
DYTYFNSGINNLLSSGEKAINFKSAEFNGFTFGGAYVFSADADKQALRDGRGFVVAGLYNRKMGDVGFAF
EAGYSQKYVKQEVEQNPPAAQKVFKDEKEKAFMVGAELSYAGLALGVDYAQSKVTNVDGKKRALEVGLNY
DLNDRAKVYTDFIWEKEGPKGDVTRNRTVAVGFGYKLHKQVETFVEAAWGREKDSDGVTTKNNVVGTGLR
VHF

Epitope Information

IEDB Linear Epitope