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FimH from E. coli str. K-12 substr. MG1655
Gene Name	FimH from E. coli str. K-12 substr. MG1655
Sequence Strain (Species/Organism)	Escherichia coli str. K-12 substr. MG1655
VO ID	VO_0010987
NCBI Gene ID	948847
NCBI Protein GI	16132141
Locus Tag	b4320
Genbank Accession	CP009685
Protein Accession	NP_418740
Taxonomy ID	511145
Gene Starting Position	4548807
Gene Ending Position	4549709
Gene Strand (Orientation)	+
Protein Name	type 1 fimbriae D-mannose specific adhesin
Protein pI	7.88
Protein Weight	27803.36
Protein Length	300
Protein Note	minor fimbrial subunit, D-mannose specific adhesin
DNA Sequence	>NC_000913.3:4548807-4549709 Escherichia coli str. K-12 substr. MG1655, complete genome AATGAAACGAGTTATTACCCTGTTTGCTGTACTGCTGATGGGCTGGTCGGTAAATGCCTGGTCATTCGCC TGTAAAACCGCCAATGGTACCGCTATCCCTATTGGCGGTGGCAGCGCCAATGTTTATGTAAACCTTGCGC CCGTCGTGAATGTGGGGCAAAACCTGGTCGTGGATCTTTCGACGCAAATCTTTTGCCATAACGATTATCC GGAAACCATTACAGACTATGTCACACTGCAACGAGGCTCGGCTTATGGCGGCGTGTTATCTAATTTTTCC GGGACCGTAAAATATAGTGGCAGTAGCTATCCATTTCCTACCACCAGCGAAACGCCGCGCGTTGTTTATA ATTCGAGAACGGATAAGCCGTGGCCGGTGGCGCTTTATTTGACGCCTGTGAGCAGTGCGGGCGGGGTGGC GATTAAAGCTGGCTCATTAATTGCCGTGCTTATTTTGCGACAGACCAACAACTATAACAGCGATGATTTC CAGTTTGTGTGGAATATTTACGCCAATAATGATGTGGTGGTGCCTACTGGCGGCTGCGATGTTTCTGCTC GTGATGTCACCGTTACTCTGCCGGACTACCCTGGTTCAGTGCCAATTCCTCTTACCGTTTATTGTGCGAA AAGCCAAAACCTGGGGTATTACCTCTCCGGCACAACCGCAGATGCGGGCAACTCGATTTTCACCAATACC GCGTCGTTTTCACCTGCACAGGGCGTCGGCGTACAGTTGACGCGCAACGGTACGATTATTCCAGCGAATA ACACGGTATCGTTAGGAGCAGTAGGGACTTCGGCGGTGAGTCTGGGATTAACGGCAAATTATGCACGTAC CGGAGGGCAGGTGACTGCAGGGAATGTGCAATCGATTATTGGCGTGACTTTTGTTTATCAATA
Protein Sequence	>NP_418740.1 type 1 fimbriae D-mannose specific adhesin [Escherichia coli str. K-12 substr. MG1655] MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPVVNVGQNLVVDLSTQIFCHNDYP ETITDYVTLQRGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVA IKAGSLIAVLILRQTNNYNSDDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAK SQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYART GGQVTAGNVQSIIGVTFVYQ
Molecule Role	Protective antigen
Molecule Role Annotation	Antibodies directed at the putative binding region of FimH (anti- s-FimH1-25) significantly reduced E. coli bladder infections in the experimental mouse model of urinary tract infections (Thankavel et al., 1997).
Related Vaccines(s)	E. coli FimH with CFA and then IFA , KLH-s-FimH1-25 with CFA and then IFA
References

FimH from E. coli str. K-12 substr. MG1655