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cadF

Gene Name cadF
Sequence Strain (Species/Organism) Campylobacter jejuni
VO ID VO_0011044
NCBI Protein GI WP_002851185
Other Database IDs CDD:275358
CDD:225439
CDD:143586
Taxonomy ID 194
Gene Strand (Orientation) ?
Protein Name fibronectin-binding outer membrane protein CadF
Protein pI 5.71
Protein Weight 36447.78
Protein Length 419
Protein Note outer membrane beta-barrel protein; TIGR04565
Protein Sequence
>WP_002851185.1 MULTISPECIES: fibronectin-binding outer membrane protein CadF [Campylobacter]
MKKIFLCLGLASVLFGADNNVKFEITPTLNYNYFEGNLDMDNRYAPGIRLGYHFDDFWLDQLEFGLEHYS
DVKYTNTNKTTDITRTYLSAIKGIDVGEKFYFYGLAGGGYEDFSNAAYDNKSGGFGHYGAGVKFRLSDSL
ALRLETRDQINFNHANHNWVSTLGISFGFGGKKEKAVEEVADTRATPQAKCPVEPREGALLDENGCEKTI
SLEGHFGFDKTTINPTFQEKIKEIAKVLDENERYDTILEGHTDNIGSRAYNQKLSERRAKSVANELEKYG
VEKSRIKTVGYGQDNPRSSNDTKEGRADNRRVDAKFILR
Molecule Role Protective antigen
Molecule Role Annotation Chitosan-DNA vaccines were prepared by embedding pcDNA3.1(+)-cadF and pcDNA3.1(+)-peblA with chitosan respectively. The mice immunized with chitosan-DNA vaccines have generated high levels of IgA and IgG from the sera and IgA from the intestinal secretions and the P/N value went up to 20.58, 30.13 and 6.87 respectively. The chitosan-DNA vaccines induced strongest level of protection in BALB/c mice against challenge with C. jejuni HS:19 strain and the protective efficacies was 93.70 (Zheng et al., 2007).
Related Vaccines(s) C. jejuni DNA vaccine pcDNA3.1(+)-cadF
References