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D8L

General Information
Protegen ID 1405
Sequence Strain (Species/Organism) Vaccinia virus
Taxonomy ID 10245
Molecule Role Protective antigen
Related Vaccines(s) Vaccinia virus DNA vaccine tPA-D8L , Vaccinia virus DNA vaccine wtD8L
References  
Gene Information
Gene Name D8L
NCBI Gene ID 3707569
Genbank Accession DQ121394
Locus Tag VACWR113
Gene Starting Position 103060
Gene Ending Position 103974
DNA Sequence 
>NC_006998.1:103060-103974 Vaccinia virus, complete genome
TCTAGTTTTGTTTTTCTCGCGAATATCGTCGACTCATAAAAAAGAGAATAGCGGTAAGTATAAACACGAA
TACTATGGCAATAATTGCGAATGTTTTATTCTCTTCGATATATTTTTGATAATATGAAAAACATGTCTCT
CTCAAATCGGACAACCATCTCATAAAATAGTTCTCGCGCGCTGGAGAGGTAGTTGCTGCTCGTATAATCT
CCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAGTTCTCTGTTATATAATG
CGGTTTTCCATCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTT
ATTGGCGTTGGAAAAATTATCCATACAGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAAT
AATCCAACTTACTAGGCAGCAAATTGTCTAGATAAAATACTGAATCAAACGGTGCAGACGTATTGGCGGA
TCTAATGGAATCCAATTGATTAACTATCTTTTGAAAATATACATTTTTATGATCCAATACTTGTAAGAAT
ATAGAAATAATGATAAGTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCC
AATGAACAAGATTAATCTCTCCAGAGTATTTGTACACATCTATCAAGTGATTGGATCCATAATCGTCTTC
CTTTCCCCAATATATATGTAGTGATGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCT
CCTTTAAAATTAATCCTTACTAGTTTTCCAGTGTTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTA
TGTCTAACGGCTTCAATCGCGCGTTAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTG
CGGCA
Protein Information
Protein Name IMV membrane protein
NCBI Protein GI 66275910
Protein Accession YP_232995
Protein pI 8.9
Protein Weight 34254.27
Protein Length 304
Protein Note similar to VACCP-D8L; binds cell surface chondroitin; may effect viral entry
Protein Sequence 
>YP_232995.1 IMV membrane protein [Vaccinia virus]
MPQQLSPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGGYISGGFLPNEYVLSSLHIYW
GKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFLQVLDHKNVYFQKIVNQLDS
IRSANTSAPFDSVFYLDNLLPSKLDYFTYLGTTINHSADAVWIIFPTPINIHSDQLSKFRTLLSSSNHDG
KPHYITENYRNPYKLNDDTQVYYSGEIIRAATTSPARENYFMRWLSDLRETCFSYYQKYIEENKTFAIIA
IVFVFILTAILFFMSRRYSREKQN
Epitope Information
IEDB Linear Epitope