18H6 synthetic E protein |
| General Information |
| Protegen ID |
1619 |
|
Sequence Strain (Species/Organism) |
synthetic construct |
|
Taxonomy ID |
32630
|
|
Other Database IDs |
CDD:279241
CDD:280922
CDD:213897 |
|
Molecule Role |
Protective antigen |
| Related Vaccines(s) |
Dengue virus DNA vaccine sABC encoding prM and E
,
Dengue virus DNA vaccine sB encoding E
|
| References |
|
| Gene Information |
|
Gene Name |
18H6 synthetic E protein |
|
NCBI Nucleotide GI |
73915390
|
|
DNA Sequence |
>gi|73915390|gb|DQ158253.1| Synthetic construct chimeric Dengue envelope antigen 18H6 mRNA, partial cds
ATGGTGGTGATCTTCATCCTGCTGATGCTGGTGACCCCCTCCATGACAATGAGGTGCGTGGGCGTGGGCA
ACAGGGACTTCGTGGAGGGCCTGAGCGGCGCCACCTGGGTGGACGTGGTGCTGGAGCACGGCGGCTGCGT
GACCACCATGGCCAAGAACAAGCCCACCCTGGACTTCGAGCTGATCAAGACCACCGCCAAGGAGGTGGCC
CTGCTGAGGACCTACTGCATCGAGGCCAGCATCAGCAACATCACCACCGCCACCAGGTGCCCCACCCAGG
GCGAGGCCATCCTGCCCGAGGAGCAGGACCAGAACTACGTGTGCAAGCACACCTACGTGGACAGGGGCTG
GGGCAACGGCTGCGGCCTGTTCGGCAAGGGCAGCCTGGTGACCTGCGCCAAGTTCACCTGCAAGAAGAAC
ATGGAGGGCAACATCGTGCAGCCCGAGAACCTGGAGTACACCATCGTGATCACCCCCCACACCGGCGACC
AGCACCAGGTGGGCAACGACACCCAGGGCGTGACCGTGGAGATCACCCCCCAGGCCAGCACCGTGGAGGC
CATCCTGCCCGAGTACGGCACCCTGGGCCTGGAGTGCAGCCCCAGGACTGGCCTGGACTTCAACAGGGTG
GTGCTGCTGACCATGAAGAAGAAGAGCTGGCTGGTGCACAAGCAGTGGTTCCTGGACCTGCCCCTGCCCT
GGACCGCCGGCGCCGACACCAGCGAGGTGCACTGGAACCACAAGGAGAGGATGGTGACCTTCAAGAACGC
CCACGCCAAGAGGCAGGACGTGACCGTGCTGGGCAGCCAGGAGGGCGCCATGCACAGCGCCCTGGCCGGC
GCCACCGAGATCCAGATGAGCAGCGGCAACCTGCTGTTCACCGGCCACCTGAAGTGCAGGCTGAAGATGG
ACAAGCTGCAGCTGAAGGGCGTGAGCTACGTGATGTGCACCGGCAGCTTCAAGCTGGAGAAGGAGGTGGC
CGAGACCCAGCACGGCACCGTGCTGGTGCAGGTGAAGTACGAGGGCACCGACGCCCCCTGCAAGATCCCC
TTCAGCACCGAGGACGGCCAGGGCAAGGCCCACAACGGCAGGCTGATCACCGTGAACCCCATCGTGATCG
ACAAGGAGAAGCCCGTGAACATCGAGCTGGAGCCCCCCTTCGGCGAGAGCTACATCGTGGTGGGCGCCGG
CGAGAAGGCCCTGAAGCTGAGCTGGTTCAAGAAGGGCAGCAGCATCGGCAAGATGTTCGAGGCCACCGCC
AGGGGCGCCAAGAGGATGGCCATCCTGGGCGAGACCGCCTGGGACTTCGGCAGCGTGGGCGGCCTGCTGA
CCAGCCTGGGCAAGGCCGTGCACCAGGTGTTCGGCGCCATCTACGGCGCC
|
| Protein Information |
|
Protein Name |
chimeric Dengue envelope antigen 18H6 |
|
NCBI Protein GI |
73915391
|
|
Protein Accession |
AAZ92557.1 |
|
Protein pI |
7.33 |
|
Protein Weight |
46583.77 |
|
Protein Length |
549 |
|
Protein Note |
derived from Dengue virus |
|
Protein Sequence |
>AAZ92557.1 chimeric Dengue envelope antigen 18H6, partial [synthetic construct]
MVVIFILLMLVTPSMTMRCVGVGNRDFVEGLSGATWVDVVLEHGGCVTTMAKNKPTLDFELIKTTAKEVA
LLRTYCIEASISNITTATRCPTQGEAILPEEQDQNYVCKHTYVDRGWGNGCGLFGKGSLVTCAKFTCKKN
MEGNIVQPENLEYTIVITPHTGDQHQVGNDTQGVTVEITPQASTVEAILPEYGTLGLECSPRTGLDFNRV
VLLTMKKKSWLVHKQWFLDLPLPWTAGADTSEVHWNHKERMVTFKNAHAKRQDVTVLGSQEGAMHSALAG
ATEIQMSSGNLLFTGHLKCRLKMDKLQLKGVSYVMCTGSFKLEKEVAETQHGTVLVQVKYEGTDAPCKIP
FSTEDGQGKAHNGRLITVNPIVIDKEKPVNIELEPPFGESYIVVGAGEKALKLSWFKKGSSIGKMFEATA
RGAKRMAILGETAWDFGSVGGLLTSLGKAVHQVFGAIYGA
|
| Vaxign Prediction |
| Localization(Probability) |
(Prob.=0) |
| Adhesin Probability |
0.519 |
| Trans-membrane Helices |
0 |
| Detailed Vaxign Results |
Vaxign Results |
| Epitope Information |
| IEDB Linear Epitope |
|
|
|
|
|
MVVIFILLMLVTPSMTMRCVGVGNRDFVEGLSGATWVDVVLEHGGCVTTMAKNKPTLDFELIKTTAKEVALLRTYCIEASISNITTATRCPTQGEAILPEEQDQNYVCKHTYVDRGWGNGCGLFGKGSLVTCAKFTCKKNMEGNIVQPENLEYTIVITPHTGDQHQVGNDTQGVTVEITPQASTVEAILPEYGTLGLECSPRTGLDFNRVVLLTMKKKSWLVHKQWFLDLPLPWTAGADTSEVHWNHKERMVTFKNAHAKRQDVTVLGSQEGAMHSALAGATEIQMSSGNLLFTGHLKCRLKMDKLQLKGVSYVMCTGSFKLEKEVAETQHGTVLVQVKYEGTDAPCKIPFSTEDGQGKAHNGRLITVNPIVIDKEKPVNIELEPPFGESYIVVGAGEKALKLSWFKKGSSIGKMFEATARGAKRMAILGETAWDFGSVGGLLTSLGKAVHQVFGAIYGA
|
