VIOLIN: Vaccine Investigation and Online Information Network

esa1

General Information

Protegen ID

1693

Sequence Strain (Species/Organism)

Edwardsiella tarda strain TX1

Taxonomy ID

636

Other Database IDs

CDD:236834
CDD:284624
CDD:279448

Molecule Role

Protective antigen

Molecule Role Annotation

Together these results indicate that Esa1 is a protective immunogen and an effective oral vaccine when delivered by FP3/pJsa1 as a surface-anchored antigen.(Sun et al., 2010)

Related Vaccines(s)

E. tarda DNA vaccine pCEsa1

References

Sun et al., 2010: Sun Y, Liu CS, Sun L. Identification of an Edwardsiella tarda surface antigen and analysis of its immunoprotective potential as a purified recombinant subunit vaccine and a surface-anchored subunit vaccine expressed by a fish commensal strain. Vaccine. 2010; 28(40); 6603-6608. [PubMed: 20673823].

Gene Information

Gene Name

esa1

Protein Information

Protein Name

putative surface antigen

NCBI Protein GI

302136428

Protein pI

5.14

Protein Weight

82376.08

Protein Length

866

Protein Note

outer membrane protein assembly factor YaeT; Provisional

Protein Sequence

>ADK94171.1 putative surface antigen [Edwardsiella tarda]
MAMKKLLLASLLFGSATVYGADGFVVKNIHFEGLQRVAVGAALLNMPVRVGDTVSDEDLSNTIRALYATG
NFEDVRVLRDGNNLIVQVKERPTIASITFSGNKSVKDEMLKQNLEASGVRVGEALDRTTLSSIEKGLEDF
YYSVGKYNATVKAVVTPLPRNRVDLKLVFTEGKSAQIQQINIVGNHAFSSAELLGHFQLRDDVPWWNLMA
DRKYQKQKLAGDLEALRSYYLDRGYARFAINSTQVSLTPDKKGIYITINITESEQYKLEGVDVTGNMAGY
SAEITRLTKVEPGELYNGAKVTKMEDEIKQLLGRYGYAYPCVQTQPEINDKDKTVVLHMNIDAGNRYYVR
QIRFVGNDTSKDAVLRREMRQMEGSWLGSDQVEQGKERLNRTGYFENVDVETQRVPGTPDQVDVIYKVKE
RNTGSFNFGIGYGTESGVSFQVGVQQDNWLGTGNVVAINGTKNDYQTYAELSLTDPYFTVNGVSLGGRLF
YNDFKANDADLSDYTNSSYGFDGTLGFPINENNSLRTGLGYVHNDLSDMQPQVAMWRYLRSVGQNPSDSQ
RASYKADDYTWTAGWAYNNLDRGFFPTAGSKASLNGKITLPGSDNEYYKLTFDSQSYFPINQDRTWVVLG
RTRLGYGNGFGGKEMPFYENFYAGGSGTVRGFQSNNIGPKAVYLNGDGSVDQSKTGDNDAVGGNAMAVAS
LELITPTPFVSEQYANSLRTSVFMDAGTVWDTNWDQAAYPTLPDYSKATNVRLSAGIALQWMSPLGPLVF
SYAQPVKKYEGDKAEQFQFNIGKTW

Epitope Information

IEDB Linear Epitope