env |
| General Information |
| Protegen ID |
1747 |
|
Sequence Strain (Species/Organism) |
Human immunodeficiency virus 1 isolate 715 from Baltimore clone 6 |
|
Taxonomy ID |
11676
|
|
Other Database IDs |
CDD:278917
CDD:295533
CDD:197369 |
|
Molecule Role |
Protective antigen |
| Related Vaccines(s) |
SHIV DNA vaccine encoding env and gag
,
SHIV(Ba-L) DNA vaccine encoding env and gag
|
| References |
|
| Gene Information |
|
Gene Name |
env |
| Protein Information |
|
Protein Name |
envelope glycoprotein |
|
NCBI Protein GI |
475647
|
|
Protein pI |
8.4 |
|
Protein Weight |
91460.08 |
|
Protein Length |
942 |
|
Protein Note |
Envelope glycoprotein GP120; pfam00516 |
|
Protein Sequence |
>AAB04079.1 envelope glycoprotein, partial [Human immunodeficiency virus 1]
VTGIRKNCQHWWKWGIMLLGILMICNATEKLWVTVYYGVPVWKEANTTLFCASDAKAYDTEVHNVWATHA
CVPTDPDPQEVELENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTNLRNDTNTTRN
ATNTTSSETMMEEGEIKNCSFNITTSIRDKVQKEFALFYKLDVVPIENDTTSYRLISCNTSVLTQACPKV
SFEPIPIHFCAPAGFAILKCKDKKFNGTGPCTNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRSANLS
DNAKTIIVQLNESVQMNCTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNLSRTKWNETLKRIVIKL
REQYENKTIVFNQSSGGDPEIVMLSFNCGGEFFYCNSTKLFNSTWNGTESNNTGDDPIVLPCRIKQVINM
WQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGNSNETNTTEIFRPGGGNMKDNWRSELYKYKVVRIEPL
GIAPTRAKRRVVQREKRAAGLGVMFLGFLGAAGSTMGAASIALTVQARQLLSGIVQQQNNLLRAIEAQQH
MLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNASWSNKSHDQIWQNMTWMQWEKE
IDNYTSLIYNLIEVSQNQQEKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFIVLSI
VNRVRQGYSPLSFQTHLPARRGPDRPEGIEEEGGERDRDRSGQLVTGFLAIIWVDLRSLCLFSYHRLRDL
LLIVARIVELLGRRGWEILKYWWNLLQYWSQELKSGAVSLLNATAIAVAEGTDRVIEVLQRAGRAILHIP
RRIRQGFERALL
|
| Epitope Information |
| IEDB Linear Epitope |
|
| IEDB ID |
Epitope |
Starting position |
Ending position |
| 174251 |
QQEKNEQELLELDKWASLWN |
648 |
668 |
| 188131 |
EIIGDIRQA |
322 |
331 |
| 188539 |
TRKSIHIGPG |
305 |
315 |
| 175628 |
NWFDIT |
667 |
673 |
| 113000 |
GIKQLQARVLAVERY |
568 |
583 |
| 158950 |
LELDKWAS |
657 |
665 |
| 26382 |
IHIGPGRAFYTT |
309 |
321 |
| 150371 |
LLELDKWASLW |
656 |
667 |
| 149298 |
ELDKWAS |
658 |
665 |
| 150180 |
EKNEQELLELDKWASLW |
650 |
667 |
| 161500 |
HIGPGRAFYT |
310 |
320 |
| 187194 |
SLWNWFDITNWLWYIK |
664 |
680 |
| 146417 |
LELDKWASL |
657 |
666 |
| 146624 |
WNWFDITN |
666 |
674 |
| 162870 |
LLELDKWA |
656 |
664 |
| 164136 |
NWFDITNWLWYIK |
667 |
680 |
| 187168 |
NEQELLELDKWASLW |
652 |
667 |
| 174184 |
LLELDKWASLW |
656 |
667 |
| 179863 |
NEQELLELDKWASLWN |
652 |
668 |
| 179922 |
WASLWNWFDITN |
662 |
674 |
| 507471 |
NWFDITNWLWYIK |
667 |
680 |
| 18911 |
GCSGKLICT |
593 |
602 |
| 226168 |
EQELLELDKWASLW |
653 |
667 |
| 434481 |
GKAMYAPPIRG |
425 |
436 |
| 433200 |
WGCSGKLICTT |
592 |
603 |
| 425283 |
HIGPGRAFY |
310 |
319 |
| 541782 |
ELDKWASLW |
658 |
667 |
| 544614 |
QQEKNEQELLELDKWASLWN |
648 |
668 |
| 146625 |
WNWFDITNW |
666 |
675 |
| 12988 |
ELDKWA |
658 |
664 |
| 745403 |
TRKSIHIGPGRAF |
305 |
318 |
| 745234 |
HIGPGRAFYTTGEI |
310 |
324 |
| 779926 |
CTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHC |
298 |
333 |
|
|
|
VTGIRKNCQHWWKWGIMLLGILMICNATEKLWVTVYYGVPVWKEANTTLFCASDAKAYDTEVHNVWATHACVPTDPDPQEVELENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTNLRNDTNTTRNATNTTSSETMMEEGEIKNCSFNITTSIRDKVQKEFALFYKLDVVPIENDTTSYRLISCNTSVLTQACPKVSFEPIPIHFCAPAGFAILKCKDKKFNGTGPCTNVSTVQCTHGIKPVVSTQLLLNGSLAEEEVVIRSANLSDNAKTIIVQLNESVQMNCTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNLSRTKWNETLKRIVIKLREQYENKTIVFNQSSGGDPEIVMLSFNCGGEFFYCNSTKLFNSTWNGTESNNTGDDPIVLPCRIKQVINMWQEVGKAMYAPPIRGQIRCSSNITGLLLTRDGGNSNETNTTEIFRPGGGNMKDNWRSELYKYKVVRIEPLGIAPTRAKRRVVQREKRAAGLGVMFLGFLGAAGSTMGAASIALTVQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTTVPWNASWSNKSHDQIWQNMTWMQWEKEIDNYTSLIYNLIEVSQNQQEKNEQELLELDKWASLWNWFDITNWLWYIKIFIMIVGGLIGLRIVFIVLSIVNRVRQGYSPLSFQTHLPARRGPDRPEGIEEEGGERDRDRSGQLVTGFLAIIWVDLRSLCLFSYHRLRDLLLIVARIVELLGRRGWEILKYWWNLLQYWSQELKSGAVSLLNATAIAVAEGTDRVIEVLQRAGRAILHIPRRIRQGFERALL
|
