env |
| General Information |
| Protegen ID |
1748 |
|
Sequence Strain (Species/Organism) |
Human immunodeficiency virus 1 strain Ba-L subtype B |
|
Taxonomy ID |
11676
|
|
Other Database IDs |
CDD:278917
CDD:295533
CDD:197369 |
|
Molecule Role |
Protective antigen |
| Related Vaccines(s) |
SHIV DNA vaccine encoding env and gag
,
SHIV(Ba-L) DNA vaccine encoding env and gag
|
| References |
|
| Gene Information |
|
Gene Name |
env |
|
NCBI Nucleotide GI |
326367
|
| Protein Information |
|
NCBI Protein GI |
326371
|
|
Protein pI |
8.87 |
|
Protein Weight |
91185.73 |
|
Protein Length |
918 |
|
Protein Note |
Envelope glycoprotein GP120; pfam00516 |
|
Protein Sequence |
>AAA44191.1 env [Human immunodeficiency virus 1]
MRVTEIRKSYQHWWRWGIMLLGILMICNAEEKLWVTVYYGVPVWKEATTTLFCASDRKAYDTEVHNVWAT
HACVPTDPNPQEVELKNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNATNGN
DTNTTSSSRGMVGGGEMKNCSFNITTNIRGKVQKEYALFYKLDIAPIDNNSNNRYRLISCNTSVITQACP
KVSFEPIPIHYCAPAGFAILKCKDKKFNGKGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSAN
FADNAKVIIVQLNESVEINCTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNLSRAKWNDTLNKIVI
KLREQFGNKTIVFKHSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWNVTEESNNTVENNTITLPCRIKQ
IINMWQEVGRAMYAPPIRGQIRCSSNITGLLLTRDGGPEDNKTEVFRPGGGDMRDNWRSELYKYKVVKIE
PLGVAPTKAKRRVVQREKRAVGIGAVFLGFLGAAGSTMGAAAMTLTVQARLLLSGIVQQQNNLLRAIEAQ
QHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTAVPWNASWSNKSLNKIWDNMTWIEWD
REINNYTSIIYSLIEESQNQQEKNEQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFSVL
SIVNRVRQGYSPLSFQTHLPSSRGPDRPGGIEEEGGERDRDRSGPLVNGFLALIWVDLRSLFLFSYHRLR
DLLLIVMRIVELLGLAGGWEVLKYWWNLLQYWSQELKNSAVSLLNATAVAVAEGTDRVIEVLQRAVRAIL
HIPRRIRQGLERALL
|
| Epitope Information |
| IEDB Linear Epitope |
|
| IEDB ID |
Epitope |
Starting position |
Ending position |
| 174251 |
QQEKNEQELLELDKWASLWN |
650 |
670 |
| 188131 |
EIIGDIRQA |
324 |
333 |
| 188539 |
TRKSIHIGPG |
307 |
317 |
| 175628 |
NWFDIT |
669 |
675 |
| 541298 |
AVGIGAVFL |
510 |
519 |
| 113000 |
GIKQLQARVLAVERY |
570 |
585 |
| 158950 |
LELDKWAS |
659 |
667 |
| 26382 |
IHIGPGRAFYTT |
311 |
323 |
| 150371 |
LLELDKWASLW |
658 |
669 |
| 149298 |
ELDKWAS |
660 |
667 |
| 150180 |
EKNEQELLELDKWASLW |
652 |
669 |
| 161500 |
HIGPGRAFYT |
312 |
322 |
| 146417 |
LELDKWASL |
659 |
668 |
| 162870 |
LLELDKWA |
658 |
666 |
| 187168 |
NEQELLELDKWASLW |
654 |
669 |
| 174184 |
LLELDKWASLW |
658 |
669 |
| 179863 |
NEQELLELDKWASLWN |
654 |
670 |
| 7214 |
CTTAVPWN |
602 |
610 |
| 18911 |
GCSGKLICT |
595 |
604 |
| 226168 |
EQELLELDKWASLW |
655 |
669 |
| 433200 |
WGCSGKLICTT |
594 |
605 |
| 425283 |
HIGPGRAFY |
312 |
321 |
| 541782 |
ELDKWASLW |
660 |
669 |
| 544614 |
QQEKNEQELLELDKWASLWN |
650 |
670 |
| 12988 |
ELDKWA |
660 |
666 |
| 566698 |
IWGCSGKLICTTAVP |
593 |
608 |
| 745647 |
SLWNWFDITKWLWYIK |
666 |
682 |
| 745403 |
TRKSIHIGPGRAF |
307 |
320 |
| 745234 |
HIGPGRAFYTTGEI |
312 |
326 |
| 779926 |
CTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHC |
300 |
335 |
| 780270 |
AVGIGAVF |
510 |
518 |
| 913291 |
GPLVN |
744 |
749 |
|
|
|
MRVTEIRKSYQHWWRWGIMLLGILMICNAEEKLWVTVYYGVPVWKEATTTLFCASDRKAYDTEVHNVWATHACVPTDPNPQEVELKNVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLRNATNGNDTNTTSSSRGMVGGGEMKNCSFNITTNIRGKVQKEYALFYKLDIAPIDNNSNNRYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGKGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSANFADNAKVIIVQLNESVEINCTRPNNNTRKSIHIGPGRAFYTTGEIIGDIRQAHCNLSRAKWNDTLNKIVIKLREQFGNKTIVFKHSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWNVTEESNNTVENNTITLPCRIKQIINMWQEVGRAMYAPPIRGQIRCSSNITGLLLTRDGGPEDNKTEVFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGAVFLGFLGAAGSTMGAAAMTLTVQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLGIWGCSGKLICTTAVPWNASWSNKSLNKIWDNMTWIEWDREINNYTSIIYSLIEESQNQQEKNEQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFSVLSIVNRVRQGYSPLSFQTHLPSSRGPDRPGGIEEEGGERDRDRSGPLVNGFLALIWVDLRSLFLFSYHRLRDLLLIVMRIVELLGLAGGWEVLKYWWNLLQYWSQELKNSAVSLLNATAVAVAEGTDRVIEVLQRAVRAILHIPRRIRQGLERALL
|
