VIOLIN: Vaccine Investigation and Online Information Network

HA

General Information

Protegen ID

527

Sequence Strain (Species/Organism)

Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))

VO ID

VO_0011121

Taxonomy ID

680785

Other Database IDs

CDD:278910

Molecule Role

Protective antigen

Molecule Role Annotation

Researchers report that a DNA vaccine encoding hemagglutinin from the index human influenza isolate A/HK/156/97 provides immunity against H5N1 infection of mice (Kodihalli et al., 1999).

Related Vaccines(s)

Influenza virus DNA vaccine encoding HA from Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))

References

Kodihalli et al., 1999: Kodihalli S, Goto H, Kobasa DL, Krauss S, Kawaoka Y, Webster RG. DNA vaccine encoding hemagglutinin provides protective immunity against H5N1 influenza virus infection in mice. Journal of virology. 1999; 73(3); 2094-2098. [PubMed: 9971791].

Gene Information

Gene Name

Protein Information

Protein Name

hemagglutinin

NCBI Protein GI

269826115

Protein pI

7.18

Protein Weight

62144.96

Protein Length

665

Protein Note

passaged in allantoic fluid

Protein Sequence

>ACZ48512.1 hemagglutinin [Influenza A virus (A/environment/Hong Kong/156/1997(H5N1))]
MEKTVLLLATVSLVKSDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILERTHNGKLCDLNGVKPLILRD
CSVAGWLLGNPMCDEFINVPEWSYIVEKASPANDLCYPGNFNDYEELKHLLSRINHFEKIQIIPKSSWSN
HDASSGVSSACPYLGRSSFFRNVVWLIKKNSAYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNP
TTYISVGTSTLNQRLVPEIATRPKVNGQSGRMEFFWTILKPNDAINFESNGNFIAPEYAYKIVKKGDSTI
MKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTIGECPKYVKSNRLVLATGLRNTPQRERRRKKRGLFG
AIAGFIEGGWQGMVDGWYGYHHSNEQGSGYAADKESTQKAIDGVTNKVNSIINKMNTQFEAVGREFNNLE
RRIENLNKKMEDGFLDVWTYNAELLVLMENERTLDFHDSNVKNLYDKVRLQLRDNAKELGNGCFEFYHKC
DNECMESVKNGTYDYPQYSEEARLNREEISGVKLESMGTYQILSIYSTVASSLALAIMVAGLSLWMCSNG
SLQCRICI

Epitope Information

IEDB Linear Epitope