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AMA-1 from P. chabaudi

General Information
Protegen ID 653
Sequence Strain (Species/Organism) Plasmodium chabaudi
VO ID VO_0011237
Taxonomy ID 5825
Other Database IDs CDD:302876
Molecule Role Protective antigen
Molecule Role Annotation Mice immunized with a refolded, recombinant, Plasmodium chabaudi AMA1 fragment (AMA1B) can withstand subsequent challenge with P. chabaudi adami (Xu et al., 2000).
Related Vaccines(s) P. chabaudi AMA1 Protein Vaccine
References
Xu et al., 2000: Xu H, Hodder AN, Yan H, Crewther PE, Anders RF, Good MF. CD4+ T cells acting independently of antibody contribute to protective immunity to Plasmodium chabaudi infection after apical membrane antigen 1 immunization. Journal of immunology (Baltimore, Md. : 1950). 2000; 165(1); 389-396. [PubMed: 10861076].
Gene Information
Gene Name AMA-1 from P. chabaudi
NCBI Gene ID 3488885
Protein Information
Protein Name apical membrane antigen 1
NCBI Protein GI 1469500
Protein pI 8.37
Protein Weight 37252.97
Protein Length 415
Protein Note DK is a cloned line derived from 556KA
Protein Sequence 
>AAB36511.1 apical membrane antigen 1, partial [Plasmodium chabaudi]
DLIPKENTERSHKLINPWEKFMEKYDIEKVHGSGIRVDLGEDARVENQDYRIPSGKCPVMGKGITIQNSK
VSFLTRVATGNQKVREGGLAFPQTDVNISPITIDNLKLMYKDHKEILALNDMSLCAKHASFYVPGTNVNT
AYRHPAVYDKSNKTCYILYVAAQENMGPRYCSNEEDNENQPFCFTPEKKDEYKNLSYLTKNLREDWETSC
PNKSIQNAKFGVWVDGYCSEYQKKEVHDNKTLLECNQIVFNESASDQPKQYEKHLEDTAKIRRGIVDRNG
KLIGEALLPIGSYRADQVKSKGKGYNWANYDKKTKKCYIFNKKPTCLINDKDFVATTALS
Epitope Information
IEDB Linear Epitope