sar5
General Information
Protegen ID
850
Sequence Strain (Species/Organism)
Streptococcus agalactiae Compton R
VO ID
VO_0012393
Taxonomy ID
1311
Other Database IDs
CDD:273479IPR001899 IPR005877 Q9XAS7
Molecule Role
Protective antigen
Molecule Role Annotation
Immunization of mice with recombinant BPS protein by the subcutaneous route produced an efficient antigen-specific response, and immunized animals survived challenge with a lethal dose of a virulent strain (Erdogan et al. , 2002 ).
Related Vaccines(s)
S. agalactiae BPS Protein Vaccine
References
Erdogan et al. , 2002: Erdogan S, Fagan PK, Talay SR, Rohde M, Ferrieri P, Flores AE, Guzmán CA, Walker MJ, Chhatwal GS. Molecular analysis of group B protective surface protein, a new cell surface protective antigen of group B streptococci. Infection and immunity . 2002; 70(2); 803-811. [PubMed: 11796614 ].
Gene Information
Gene Name
sar5
Protein Information
Protein Name
BPS protein
NCBI Protein GI
5327234
Protein pI
4.92
Protein Weight
96916.55
Protein Length
1045
Protein Note
Gram-positive signal peptide, YSIRK family; TIGR01168
Protein Sequence
>CAB46338.1 BPS protein [Streptococcus agalactiae]
MFRQYNFEKGLNFSIRKFSVGIASVAIGSLLFILPQVLADETTSVTSATTPTGVTTTDANLVNPNNSTPT
STNRSATSTQGSNLSNTSEIIKPATLAATSPTTDNVAPSVDKRTYATSGDWTLQNPYADSVRNKNISPSV
RHESFKSAETTVVRHDNSTVKVTATITPVEGNDEGSGILTNGGNQSEYKATSEMFVGNVDPAKIPALGVY
TQPGRTEGGSKLSDKLNFNGKAPSTILTLKFDKAVTDPIIDLSGVGGNARLSFTETVMENGKIVEKFDYA
RGSYNSTFFDGITPGISLEKASSGVNLTVTANTVDVTDKNTFNESVVNPSDEDFVNGPDRTPDAVPAGTG
SIRLKGTFTDASFKLYHQAVPSTAFSKEKYHTGDGYYNSIANVRPTVVKPDSINGLNKHASDVIDYKISD
NNDISNDDLLRLSVRLQNPRGSVVVNYIDTEGNIIGTEYKDTTDAIPGTHYNTAESSGDLNSDATVERPS
TITKDGKVYDLVAENITVPVGKVNSDGTLATNGSSFNYGTDAASAEVAEGTKSVIYVISIKQESKGNVHA
RYVILGTETELASAKTVKSEAPIDEAYSDKAPATLEKDGKLYEFVHVRDNKGDAPADGKVTEQDQTITYE
YVEVPKGRVVVDYVIEGTATKPKDTYVDTPTAYIRDKEGQAIPYNTAENDSEKPLLLDKDGIKYELVSIQ
EGSAAEKGTLREGEQHVVYQYRKVVEVPSVKVGNVHARYVILGTETELASAKTVKSEAPIDEAYSDKAPA
TLEKDGKLYEFVHVRDNKGDAPADGKVTEQDQTITYEYKLKKDDADAVGNVVINYVDETGNVIKKPILDT
HESKVGTPYDTTDYKFAEIKFNGKIYKLVSAKTMGNEFGKVTEGTTEVTYVYRESVKSTLPKETGISIPS
ESESPKFISTQTTENRPNKGVLTSSKNPTNKSVLPTTGEESNRILGVVGITLVATTATLAASSLKRRKN
Epitope Information
IEDB Linear Epitope
-- Assay Type --
T Cell Epitope
B Cell Epitope
IEDB ID
Epitope
MHC restriction
Starting position
Ending position
IEDB ID
Epitope
Starting position
Ending position
1168 AESSG
474
479
MFRQYNFEKGLNFSIRKFSVGIASVAIGSLLFILPQVLADETTSVTSATTPTGVTTTDANLVNPNNSTPTSTNRSATSTQGSNLSNTSEIIKPATLAATSPTTDNVAPSVDKRTYATSGDWTLQNPYADSVRNKNISPSVRHESFKSAETTVVRHDNSTVKVTATITPVEGNDEGSGILTNGGNQSEYKATSEMFVGNVDPAKIPALGVYTQPGRTEGGSKLSDKLNFNGKAPSTILTLKFDKAVTDPIIDLSGVGGNARLSFTETVMENGKIVEKFDYARGSYNSTFFDGITPGISLEKASSGVNLTVTANTVDVTDKNTFNESVVNPSDEDFVNGPDRTPDAVPAGTGSIRLKGTFTDASFKLYHQAVPSTAFSKEKYHTGDGYYNSIANVRPTVVKPDSINGLNKHASDVIDYKISDNNDISNDDLLRLSVRLQNPRGSVVVNYIDTEGNIIGTEYKDTTDAIPGTHYNTAESSGDLNSDATVERPSTITKDGKVYDLVAENITVPVGKVNSDGTLATNGSSFNYGTDAASAEVAEGTKSVIYVISIKQESKGNVHARYVILGTETELASAKTVKSEAPIDEAYSDKAPATLEKDGKLYEFVHVRDNKGDAPADGKVTEQDQTITYEYVEVPKGRVVVDYVIEGTATKPKDTYVDTPTAYIRDKEGQAIPYNTAENDSEKPLLLDKDGIKYELVSIQEGSAAEKGTLREGEQHVVYQYRKVVEVPSVKVGNVHARYVILGTETELASAKTVKSEAPIDEAYSDKAPATLEKDGKLYEFVHVRDNKGDAPADGKVTEQDQTITYEYKLKKDDADAVGNVVINYVDETGNVIKKPILDTHESKVGTPYDTTDYKFAEIKFNGKIYKLVSAKTMGNEFGKVTEGTTEVTYVYRESVKSTLPKETGISIPSESESPKFISTQTTENRPNKGVLTSSKNPTNKSVLPTTGEESNRILGVVGITLVATTATLAASSLKRRKN
